Polymer Synthesis and Preparation for Tissue Scaffolds: A handbook for polymer choice, design properties and fabrication techniques - Couverture souple

Başar, Başak

 
9783639631005: Polymer Synthesis and Preparation for Tissue Scaffolds: A handbook for polymer choice, design properties and fabrication techniques
Couverture souple
ISBN 10 : 3639631005 ISBN 13 : 9783639631005
Editeur : AV Akademikerverlag, 2014

Synopsis

The tissue engineering concept is based on cells, typically taken from a patient, multiplied in number, and seeded on a scaffold. The main function of a tissue engineered-scaffold has to fulfill mimicking the ECM characteristics and properties in native tissues. Briefly, the scaffold is a 3D substrate and serves as a template for tissue regeneration. Model scaffolds should have some features to accomplish the fundamental demands of a target tissue, namely having an appropriate surface chemistry and microstructure to ease the cellular attachment, proliferation, differentiation, and obtaining an acceptable mechanical strength, biodegradation rate, and biocompatibility. This book aims to review most of the critically valuable issues related to scaffold design, polymer choice and general requirements for ideal scaffolds, scaffold fabrication techniques, and polymer synthesis methods. Surface characteristics of commonly used polymers (PLA, PGA, and PLGA) are summarized. Furthermore, scaffold fabrication techniques are deeply analyzed; benefits and obstacles of the techniques are compared. Polymers for tissue-engineered scaffolds are discussed with respective of synthesis techniques, suitability, compatibility to the scaffold's architecture, such as pore size and size distributions. Effects of the architecture on the cells' growth are also examined.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The tissue engineering concept is based on cells, typically taken from a patient, multiplied in number, and seeded on a scaffold. The main function of a tissue engineered-scaffold has to fulfill mimicking the ECM characteristics and properties in native tissues. Briefly, the scaffold is a 3D substrate and serves as a template for tissue regeneration. Model scaffolds should have some features to accomplish the fundamental demands of a target tissue, namely having an appropriate surface chemistry and microstructure to ease the cellular attachment, proliferation, differentiation, and obtaining an acceptable mechanical strength, biodegradation rate, and biocompatibility. This book aims to review most of the critically valuable issues related to scaffold design, polymer choice and general requirements for ideal scaffolds, scaffold fabrication techniques, and polymer synthesis methods. Surface characteristics of commonly used polymers (PLA, PGA, and PLGA) are summarized. Furthermore, scaffold fabrication techniques are deeply analyzed; benefits and obstacles of the techniques are compared. Polymers for tissue-engineered scaffolds are discussed with respective of synthesis techniques, suitability, compatibility to the scaffold's architecture, such as pore size and size distributions. Effects of the architecture on the cells' growth are also examined.

Biographie de l'auteur

Başak Başar was born in Ankara, Turkey. After successfully completing her bachelor's studies in biomedical engineering, she moved to Germany in order to begin a master's program in the same field. Her master's thesis on scaffold production techniques followed her extensive research on tissue engineering in Germany and forms the basis of this book.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
AV Akademikerverlag
Date d'édition
2014
Langue
anglais
ISBN 10 
3639631005
ISBN 13 
9783639631005
Reliure
Broché
Nombre de pages
92
Coordonnées du fabricant
non disponible
Personne responsable
non disponible