Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of oligonucleotides and oligonucleotide conjugates have been reported. The subjects of medicinal chemical programmes include approaches to create enhanced affinity and more selective affinity for RNA or duplex structures, the ability to cleave nucleic acid targets, enhanced nuclease stability, cellularuptake and distribution, in vivo tissue distribution, metabolism and clearance.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of oligonucleotides and oligonucleotide conjugates have been reported. The subjects of medicinal chemical programmes include approaches to create enhanced affinity and more selective affinity for RNA or duplex structures, the ability to cleave nucleic acid targets, enhanced nuclease stability, cellularuptake and distribution, in vivo tissue distribution, metabolism and clearance.
Dr. Kartik B. Vyas M. Sc. , Ph. D.,(Chemistry) F. I. C. C.,F. I. C. S. professor, Sheth L. H. Science College,Mansa, Gujarat(India). Ten students completed theirPh. D. Degree by his guidance.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of oligonucleotides and oligonucleotide conjugates have been reported. The subjects of medicinal chemical programmes include approaches to create enhanced affinity and more selective affinity for RNA or duplex structures, the ability to cleave nucleic acid targets, enhanced nuclease stability, cellularuptake and distribution, in vivo tissue distribution, metabolism and clearance. 124 pp. Englisch. N° de réf. du vendeur 9783639713855
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vyas KartikDr. Kartik B. Vyas M. Sc. , Ph. D.,(Chemistry) F. I. C. C.,F. I. C. S. professor, Sheth L. H. Science College,Mansa, Gujarat(India). Ten students completed theirPh. D. Degree by his guidance.Generally pyrimidine deriv. N° de réf. du vendeur 4999523
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Taschenbuch. Etat : Neu. Neuware -Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of oligonucleotides and oligonucleotide conjugates have been reported. The subjects of medicinal chemical programmes include approaches to create enhanced affinity and more selective affinity for RNA or duplex structures, the ability to cleave nucleic acid targets, enhanced nuclease stability, cellularuptake and distribution, in vivo tissue distribution, metabolism and clearance.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 124 pp. Englisch. N° de réf. du vendeur 9783639713855
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Generally pyrimidine derivatives such as 2-hydroxy-substitutedpyrimidine, 2-mercapto-substituted-pyrimidine and 2-amino-substituted pyrimidine are studied. Pyrimidines have been isolated from the nucleic acid hydrolysates. Pyrimidines are among those molecules that make life possible, have been some of the building blocks of DNA and RNA. Several analogues of pyrimidines have been used as compounds that interfere with the synthesis and functioning of nucleic acids e.g. fluorouracil, which has been used in cancer treatment. Modifications in the base, sugar and phosphate moieties of oligonucleotides and oligonucleotide conjugates have been reported. The subjects of medicinal chemical programmes include approaches to create enhanced affinity and more selective affinity for RNA or duplex structures, the ability to cleave nucleic acid targets, enhanced nuclease stability, cellularuptake and distribution, in vivo tissue distribution, metabolism and clearance. N° de réf. du vendeur 9783639713855
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Taschenbuch. Etat : Neu. Tetrahydro Pyrimidines | Kartik Vyas (u. a.) | Taschenbuch | 124 S. | Englisch | 2014 | Scholars' Press | EAN 9783639713855 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. N° de réf. du vendeur 105323658
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