Le diabète sucré (DM) est une endémie mondiale avec une prévalence croissante dans les pays en développement et développés dans une cause fréquente d'invalidité et de décès partout dans le monde. L'explosion de diabète dans le monde est principalement due au diabète de type 2 environ (90 à 95 %). Son étiologie spécifique n'est pas encore connue, sa fréquence varie selon les sous-groupes raciaux et ethniques et est souvent associée à une forte prédisposition génétique familiale et probable. Il a été indiqué que le DM de type 2 était associé à certains allèles HLA de classe II ont été analysés pour leur génotypage par polymérase Chain Reaction-Sequences Specific Olegionucleotide (PCR-SSO) technique. La présente étude a révélé que les patients diabétiques étaient positivement associés à HLA-DQB1*0201 (83 % contre 5,0 %), qui est le plus répandu chez les patients suivis de DRB1*1137 (46,7 % vs 0,0 %); DRB1*0401 (41,7 % contre 2 %). 0,5 %), et DRB1*1306 (15% vs.0.0%) tandis que HLA,A*0201;B*3559;Cw*0410 et DQB1*0501 est négativement associé dans le type 2DM par rapport aux groupes témoins sains. Cette étude a montré qu'il n'y a pas d'association significative entre le FBS, l'HbA1c, l'insuline sérique, la fonction HOMA2, HOMA2-IR, l'adiponectine sérique, l'adénosine désaminase sérique et les allèles HLA.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Diabetes mellitus (DM) is a world-wide endemic with increasing prevalence in both developing and developed countries in a common cause of disability and death all over the world .The outburst of diabetes in the word is mainly due to type 2 diabetes about (90 - 95%). Its specific etiology is not yet known its frequency varies in different racial and ethnic subgroups and is often associated with a strong familial, likely genetic predisposition. It was denoted that type2 DM was associated with certain HLA class II alleles were analyzed for their genotyping by Polymerase Chain Reaction-Sequences Specific Olegionucleotide (PCR-SSO) technique. The present study revealed that diabetic patients were positively associated with HLA-DQB1\*0201 (83% vs. 5.0%) which is the most prevalent in patients followed by DRB1\*1137 (46.7% vs. 0.0%); DRB1\*0401 (41.7% vs. 2.5%),and DRB1\*1306(15% vs.0.0%) while HLA,A\*0201;B\*3559;Cw\*0410 and DQB1\*0501 is negatively associated in type 2DM in comparison to healthy control groups. This study has shown that there is no significant association between FBS,HbA1c,serum insulin,HOMA2 beta-function , HOMA2-IR ,serum adiponectin ,serum adenosine deaminase and HLA alleles . 136 pp. Englisch. N° de réf. du vendeur 9783639766813
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kadhim Mohammed AhmedDoctor Ahmed Kadhim Mohammed is Chief Lab technologist at Ministry of Health / Iraqi Medical Legal Institute.Diabetes mellitus (DM) is a world-wide endemic with increasing prevalence in both developing and de. N° de réf. du vendeur 151401247
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Diabetes mellitus (DM) is a world-wide endemic with increasing prevalence in both developing and developed countries in a common cause of disability and death all over the world .The outburst of diabetes in the word is mainly due to type 2 diabetes about (90 - 95%). Its specific etiology is not yet known its frequency varies in different racial and ethnic subgroups and is often associated with a strong familial, likely genetic predisposition. It was denoted that type2 DM was associated with certain HLA class II alleles were analyzed for their genotyping by Polymerase Chain Reaction-Sequences Specific Olegionucleotide (PCR-SSO) technique. The present study revealed that diabetic patients were positively associated with HLA-DQB1\*0201 (83% vs. 5.0%) which is the most prevalent in patients followed by DRB1\*1137 (46.7% vs. 0.0%); DRB1\*0401 (41.7% vs. 2.5%),and DRB1\*1306(15% vs.0.0%) while HLA,A\*0201;B\*3559;Cw\*0410 and DQB1\*0501 is negatively associated in type 2DM in comparison to healthy control groups. This study has shown that there is no significant association between FBS,HbA1c,serum insulin,HOMA2 ß-function , HOMA2-IR ,serum adiponectin ,serum adenosine deaminase and HLA alleles .VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 136 pp. Englisch. N° de réf. du vendeur 9783639766813
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Diabetes mellitus (DM) is a world-wide endemic with increasing prevalence in both developing and developed countries in a common cause of disability and death all over the world .The outburst of diabetes in the word is mainly due to type 2 diabetes about (90 - 95%). Its specific etiology is not yet known its frequency varies in different racial and ethnic subgroups and is often associated with a strong familial, likely genetic predisposition. It was denoted that type2 DM was associated with certain HLA class II alleles were analyzed for their genotyping by Polymerase Chain Reaction-Sequences Specific Olegionucleotide (PCR-SSO) technique. The present study revealed that diabetic patients were positively associated with HLA-DQB1\*0201 (83% vs. 5.0%) which is the most prevalent in patients followed by DRB1\*1137 (46.7% vs. 0.0%); DRB1\*0401 (41.7% vs. 2.5%),and DRB1\*1306(15% vs.0.0%) while HLA,A\*0201;B\*3559;Cw\*0410 and DQB1\*0501 is negatively associated in type 2DM in comparison to healthy control groups. This study has shown that there is no significant association between FBS,HbA1c,serum insulin,HOMA2 beta-function , HOMA2-IR ,serum adiponectin ,serum adenosine deaminase and HLA alleles . N° de réf. du vendeur 9783639766813
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