Histomorphometric, Histochemical and DNA Quantitative Analysis of OSCC - Couverture souple

Al - Azzawi, Lehadh; Al - Talabani, Nazar; Al - Salihi, Anam

 
9783639767858: Histomorphometric, Histochemical and DNA Quantitative Analysis of OSCC
Couverture souple
ISBN 10 : 3639767853 ISBN 13 : 9783639767858
Editeur : Scholars' Press, 2015

Synopsis

The objective of the present study was designed to establish more specific criteria for the degree of differentiation and nuclear DNA histochemical quantitation of OSCC. Morphometric measurements by image analysis computer system and DNA histochemical quantitative analysis were assessed in association with clinicopathological features of OSCC. Two histological grading systems were used; Broders’ grading system & Invasive front grading system using four histomorphological features that includes; degree of keratinization, nuclear pleomorphism, pattern of invasion and host response (inflammatory cell infiltration). The morphometric measurement was carried out using H&E staining techniques. Each nucleus and cell was submitted to morphometric parameter measurements that include nuclear area, maximum diameter (D max), form AR and D circle, cellular morphometric perimeter and nucleo: cytoplasmic ratio. A microspectrophotmerty technique was used to determine the quality of tumour nuclear DNA content with both histological grading systems of OSCC that stained by Feulgen reaction. Esterases histochemistry was employed to evaluate the distribution of carboxyl ester hydrolases in OSCC.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The objective of the present study was designed to establish more specific criteria for the degree of differentiation and nuclear DNA histochemical quantitation of OSCC. Morphometric measurements by image analysis computer system and DNA histochemical quantitative analysis were assessed in association with clinicopathological features of OSCC. Two histological grading systems were used; Broders’ grading system & Invasive front grading system using four histomorphological features that includes; degree of keratinization, nuclear pleomorphism, pattern of invasion and host response (inflammatory cell infiltration). The morphometric measurement was carried out using H&E staining techniques. Each nucleus and cell was submitted to morphometric parameter measurements that include nuclear area, maximum diameter (D max), form AR and D circle, cellular morphometric perimeter and nucleo: cytoplasmic ratio. A microspectrophotmerty technique was used to determine the quality of tumour nuclear DNA content with both histological grading systems of OSCC that stained by Feulgen reaction. Esterases histochemistry was employed to evaluate the distribution of carboxyl ester hydrolases in OSCC.

Biographie de l'auteur

Dr.Lehadh Al-Azzawi has obtained her PhD degree in oral pathology in 2003.since she has worked in different projects in this field;OSCC,salivary gland tumours and histologic evaluation of laser application in Dentistry.she is the author of several articles published in journal and a supervisor and member of several examining committee certification.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Scholars' Press
Date d'édition
2015
Langue
anglais
ISBN 10 
3639767853
ISBN 13 
9783639767858
Reliure
Broché
Nombre de pages
192
Coordonnées du fabricant
non disponible
Personne responsable
non disponible