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This is an overview of recent progress in magnetic particle imaging, which uses various static and oscillating magnetic fields and tracer materials made from iron oxide nanoparticles to perform background-free measurements of the particles' local concentration.
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THORSTEN M. BUZUG was born in Luebeck, Germany, in 1963. He received his Diplom-Physiker degree in 1989 and his Ph.D. in 1993 in Applied Physics both from the Christian-Albrechts-University of Kiel, Germany, where he worked in the field of signal processing applied to chaotic systems. From 1993 to 1994 he had a postdoctoral position at the German Federal Armed Forces Underwater Acoustics and Marine Geophysics Research Institute, where he worked on image acquisition and processing techniques for SONAR applications. In the end of 1994 he joined the Philips Research Laboratories Hamburg, Germany. He was the leader of the Philips Research Cluster Medical Image Processing and responsible for several projects in that field. He has published numerous journal articles, conference papers and books. In October 1998 he was appointed as professor of Physics and Medical Engineering at the RheinAhrCampus Remagen. 2000-2004 he was head of the Academic Development Committee of the RheinAhrCampus Remagen. 2004-2006 he was head of the Joint Council of Campus Departments. In December 2006 he became Director of the Institute of Medical Engeneering at the University of Luebeck.
This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.
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