Behavioral Neurobiology of the Endocannabinoid System - Couverture souple

Couverture souple

ISBN 10 : 3642260780 ISBN 13 : 9783642260780

Editeur : Springer, 2012

Synopsis

. . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 StephenP. H. AlexanderandDavidA. Kendall 2 EndocannabinoidReceptorPharmacology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 KenMackieandBettyYao 3 EndocannabinoidReceptors:CNSLocalizationoftheCB 1 CannabinoidReceptor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65 Istva´nKatona 4 PharmacologicalToolsinEndocannabinoidNeurobiology. . . . . . . . . . . . . . 87 MarcoMorandAlessioLodola 5 GeneticModelsoftheEndocannabinoidSystem . . . . . . . . . . . . . . . . . . . . . . . 111 KrisztinaMonoryandBeatLutz 6 EndocannabinoidSignalinginNeuralPlasticity . . . . . . . . . . . . . . . . . . . . . . . 141 BradleyE. Alger 7 LessonsfromNonmammalianSpecies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 KenSoderstrom PartII PhysiologyandPathophysiology 8 RolesoftheEndocannabinoidSysteminLearning andMemory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 201 ˆ GiovanniMarsicanoandPaulineLafenetre vii viii Contents 9 EndocannabinoidsandtheNon-HomeostaticControl ofAppetite . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 231 TimC. Kirkham 10 Cannabinoid/EndocannabinoidSignalingImpactonEarly PregnancyEvents. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 255 XiaofeiSunandSudhansuK. Dey 11 TargetingtheCannabinoidSystemtoProduceAnalgesia . . . . . . . . . . . 275 DeviRaniSagar,MaulikJhaveri,andVictoriaChapman 12 IntegrationofEndocannabinoidSignalingintotheNeural NetworkRegulatingStress-InducedActivationofthe Hypothalamic–Pituitary–AdrenalAxis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289 BorisB. GorzalkaandMatthewN. Hill PartIII Pathology 13 DrugAddiction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 309 ZuzanaJustinova,LeighV. Panlilio,andStevenR. Goldberg 14 RoleofEndocannabinoidSignalinginAnxietyandDepression. . . . . 347 SachinPatelandCeciliaJ. Hillard 15 FeedingDisordersandObesity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 373 CristinaCervino,ValentinaVicennati,RenatoPasquali, andUbertoPagotto 16 Schizophrenia. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 F. Markus 17 Tourette’sSyndrome. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397 KirstenR. Mu¨ller-Vahl Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 Contributors StephenP. H. Alexander SchoolofBiomedicalSciencesandInstituteofNeuroscience,UniversityofN- tingham Medical School, Queens Medical Centre, Nottingham NG7 2UH, UK; steve. alexander@nottingham. ac. uk BradleyE. Alger Departments of Physiology and Psychiatry, University of Maryland School of Medicine, 655 W. Baltimore St. /BRB 5-025, Baltimore, MD 21201, USA; balger@umaryland. edu CristinaCervino Endocrinology Unit and Center of Applied Biomedical Research (C. R. B. A. ), DepartmentofInternalMedicineandGastroenterology,S. Orsola-MalpighiHos- tal,AlmaMaterStudiorumUniversityofBologna,40138Bologna,Italy VictoriaChapman SchoolofBiomedicalSciences,UniversityofNottingham,NottinghamNG72UH, UK;victoria. chapman@nottingham. ac. uk SudhansuK. Dey Departments of Pharmacology, Pediatrics and Cell & Developmental Biology, Division of Reproductive and Developmental Biology, Vanderbilt University MedicalCenter,Nashville,TN37232,USA;sk. dey@vanderbilt. edu StevenR.

A propos du livre

À propos de la quatrième de couverture

<p>The endocannabinoid signalling system is one of the key modulators of central nervous function. This volume provides timely and in-depth coverage of the roles of the endocannabinoid signalling system in the neurobiology of behavior. It is essential reading for any researcher with a background in neuroscience wanting to know more about the endocannabinoids. The first section provides a comprehensive account of the component parts of the system (the signalling molecules, synthetic and degradative enzymes and receptors), their location within the central nervous system and the endocannabinoids’ roles in neural plasticity. This section also describes the toolboxes (genetic and pharmacological) used to study the system. The second section concentrates on endocannabinoid function in the control of normal physiological behaviors including a reference to the evolution of the system based on its operation in non-mammalian vertebrates. The volume concludes by addressing the importance of the endocannabinoids in pathological behaviors including affective and cognitive disorders, neurodegenerative conditions, feeding and drug abuse. </p>

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 3642260780
• ISBN 13: 9783642260780
• Reliure: Broché
• Nombre de pages: 418
• Éditeur: Kendall Dave, Alexander Stephen
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne