This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The silencing of gene expression by small interfering RNAs has been recognized for only a relatively short time, but this has transformed our understanding of both transcriptional and post-transcriptional gene regulatory mechanisms. Multiple pathways culminate in formation of an RNA-induced silencing complex (RISC) containing a member of the Argonaute protein family bound to a 22-nt RNA strand that interacts with a target mRNA or gene through Watson-Crick base pairing. One consequence is mRNA-specific inhibition of protein synthesis. Evidence has been presented for diverse mechanisms, but there is not universal agreement in the field of how RISCs affect the translational machinery. The chapters collected in this volume represent contribution by leaders in the search to understand how miRNAs affect translation. They include chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs, but also include chapters on mammalian systems, with special emphasis on regulation of a key tumor suppressor and a protein that restricts human immunodeficiency virus 1 (HIV-1). 128 pp. Englisch. N° de réf. du vendeur 9783642261404
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Up-to-day findings on influence of miRNAs on gene translationGives an overview on different microRNA types and functions in plants and animalsShows novel applications of microRNAsUnderstanding How miRNAs Post-Transcriptionally Regul. N° de réf. du vendeur 5054214
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Taschenbuch. Etat : Neu. miRNA Regulation of the Translational Machinery | Robert E. Rhoads | Taschenbuch | Progress in Molecular and Subcellular Biology | x | Englisch | 2012 | Springer | EAN 9783642261404 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 106590991
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Understanding How miRNAs Post-Transcriptionally Regulate Gene Expression.- Translational Control of Endogenous MicroRNA Target Genes in.- Translational Inhibition by MicroRNAs in Plants.- Regulation of p27 mRNA Expression by MicroRNAs.- The Inhibitory Effect of Apolipoprotein B mRNA-Editing Enzyme Catalytic Polypeptide-Like 3G (APOBEC3G) and Its Family Members on the Activity of Cellular MicroRNAs.- MicroRNA-Mediated mRNA Deadenylation and Repression of Protein Synthesis in a Mammalian Cell-Free System.- miRNA Effects on mRNA Closed-Loop Formation During Translation Initiation.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 128 pp. Englisch. N° de réf. du vendeur 9783642261404
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The silencing of gene expression by small interfering RNAs has been recognized for only a relatively short time, but this has transformed our understanding of both transcriptional and post-transcriptional gene regulatory mechanisms. Multiple pathways culminate in formation of an RNA-induced silencing complex (RISC) containing a member of the Argonaute protein family bound to a 22-nt RNA strand that interacts with a target mRNA or gene through Watson-Crick base pairing. One consequence is mRNA-specific inhibition of protein synthesis. Evidence has been presented for diverse mechanisms, but there is not universal agreement in the field of how RISCs affect the translational machinery. The chapters collected in this volume represent contribution by leaders in the search to understand how miRNAs affect translation. They include chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs, but also include chapters on mammalian systems, with special emphasis on regulation of a key tumor suppressor and a protein that restricts human immunodeficiency virus 1 (HIV-1). N° de réf. du vendeur 9783642261404
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