The Extracellular Matrix: an Overview: An Overview (Biology of Extracellular Matrix) - Couverture souple

Couverture souple

ISBN 10 : 364226719X ISBN 13 : 9783642267192

Editeur : Springer, 2013

Synopsis

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling.

This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

A propos du livre

Présentation de l'éditeur

Covering a wide spectrum of topics including collagen types and the role of the ECM in human disease and pathogenesis, this volume is a timely overview of the structure, regulation, and function of the major macromolecules that form the extracellular matrix.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 364226719X
• ISBN 13: 9783642267192
• Reliure: Broché
• Nombre de pages: 440
• Éditeur: Mecham Robert
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne