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Synopsis
Framed by a statistical physics perspective, this volume describes both the process of self-assembly and the impact of spatial organization on the function of membrane proteins. Using methods from equilibrium and non-equilibrium statistical mechanics, the text demonstrates the importance of the protein-protein interactions.
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Framed by a statistical physics perspective, this volume describes both the process of self-assembly and the impact of spatial organization on the function of membrane proteins. Using methods from equilibrium and non-equilibrium statistical mechanics, the text demonstrates the importance of the protein-protein interactions.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane (Springer Theses)
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane (Paperback)
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Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin, 2013
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ISBN 13 : 9783642269943
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Paperback. Etat : new. Paperback. With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly of membrane proteins, the collective response of mechanosensitive channels and the function of the twin arginine translocation (Tat) system. Using methods from equilibrium and non-equilibrium statistical mechanics, general conclusions were drawn that demonstrate the importance of the protein-protein interactions. Namely, in the first part a general aggregation dynamics model is formulated, and used to show that fragmentation crucially affects the efficiency of the self-assembly process of proteins. In the second part, by mapping the membrane-mediated forces into a simplified many-body system, the dynamic and equilibrium behaviour of interacting mechanosensitive channels is derived, showing that protein agglomeration strongly impacts its desired function. The final part develops a model that incorporates both the agglomeration and transport function of the Tat system, thereby providing a comprehensive description of this self-organizing process. With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. N° de réf. du vendeur 9783642269943
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane (Springer Theses)
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
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Springer Berlin Heidelberg Nov 2013, 2013
ISBN 10 : 364226994X
ISBN 13 : 9783642269943
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly of membrane proteins, the collective response of mechanosensitive channels and the function of the twin arginine translocation (Tat) system. Using methods from equilibrium and non-equilibrium statistical mechanics, general conclusions were drawn that demonstrate the importance of the protein-protein interactions. Namely, in the first part a general aggregation dynamics model is formulated, and used to show that fragmentation crucially affects the efficiency of the self-assembly process of proteins. In the second part, by mapping the membrane-mediated forces into a simplified many-body system, the dynamic and equilibrium behaviour of interacting mechanosensitive channels is derived, showing that protein agglomeration strongly impacts its desired function. The final part develops a model that incorporates both the agglomeration and transport function of the Tat system, thereby providing a comprehensive description of this self-organizing process. 92 pp. Englisch. N° de réf. du vendeur 9783642269943
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
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Springer Berlin Heidelberg, 2013
ISBN 10 : 364226994X
ISBN 13 : 9783642269943
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Nominated as an outstanding contribution by the University of Aberdeen Contains essential new results on the statistical mechanics and dynamics of macromolecular assembly Yields important conclusions and predictions for biological membranes . N° de réf. du vendeur 5055033
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane (Springer Theses)
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Paperback. Etat : Brand New. 2012 edition. 110 pages. 9.25x6.10x0.21 inches. In Stock. N° de réf. du vendeur x-364226994X
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
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Springer Berlin Heidelberg, Springer Berlin Heidelberg Nov 2013, 2013
ISBN 10 : 364226994X
ISBN 13 : 9783642269943
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Taschenbuch
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly of membrane proteins, the collective response of mechanosensitive channels and the function of the twin arginine translocation (Tat) system. Using methods from equilibrium and non-equilibrium statistical mechanics, general conclusions were drawn that demonstrate the importance of the protein-protein interactions. Namely, in the first part a general aggregation dynamics model is formulated, and used to show that fragmentation crucially affects the efficiency of the self-assembly process of proteins. In the second part, by mapping the membrane-mediated forces into a simplified many-body system, the dynamic and equilibrium behaviour of interacting mechanosensitive channels is derived, showing that protein agglomeration strongly impacts its desired function. The final part develops a model that incorporates both the agglomeration and transport function of the Tat system, thereby providing a comprehensive description of this self-organizing process.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 92 pp. Englisch. N° de réf. du vendeur 9783642269943
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane
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Springer Berlin Heidelberg, 2013
ISBN 10 : 364226994X
ISBN 13 : 9783642269943
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - With the aim of providing a deeper insight into possible mechanisms of biological self-organization, this thesis presents new approaches to describe the process of self-assembly and the impact of spatial organization on the function of membrane proteins, from a statistical physics point of view. It focuses on three important scenarios: the assembly of membrane proteins, the collective response of mechanosensitive channels and the function of the twin arginine translocation (Tat) system. Using methods from equilibrium and non-equilibrium statistical mechanics, general conclusions were drawn that demonstrate the importance of the protein-protein interactions. Namely, in the first part a general aggregation dynamics model is formulated, and used to show that fragmentation crucially affects the efficiency of the self-assembly process of proteins. In the second part, by mapping the membrane-mediated forces into a simplified many-body system, the dynamic and equilibrium behaviour of interacting mechanosensitive channels is derived, showing that protein agglomeration strongly impacts its desired function. The final part develops a model that incorporates both the agglomeration and transport function of the Tat system, thereby providing a comprehensive description of this self-organizing process. N° de réf. du vendeur 9783642269943
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Formation and Cooperative Behaviour of Protein Complexes on the Cell Membrane (Springer Theses)
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Springer, 2013
ISBN 10 : 364226994X
ISBN 13 : 9783642269943
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