This book examines the present and future of drug discovery at protein-protein interfaces. It details computational and experimental tools used in the field, and offers examples of drug-like molecules effective in interacting at protein-protein interfaces.
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Stefano Mangani has been professor of general and inorganic chemistry at the University of Siena since 1994. His main field of research is bioinorganic chemistry and structural biology and he currently focuses on the role of metal ions in metalloenzyme catalysis and in metalloproteins, with particular emphasis on the chemistry occurring at the metal sites as revealed by accurate structural data. Professor Mangani is regularly invited to speak at international conferences and seminars. He is the author of over 140 publications in international scientific journals and book series and has also written a general and inorganic university textbook and a web-course on general chemistry.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Disruption of Protein-Protein Interfaces' reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces. 172 pp. Englisch. N° de réf. du vendeur 9783642433894
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides an overview of the present state and future perspectives of drug discovery at protein-protein interfacesGives details of both computational and experimental tools used in the fieldGives positive examples of drug-like molecules effe. N° de réf. du vendeur 449056344
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - 'Disruption of Protein-Protein Interfaces' reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces. N° de réf. du vendeur 9783642433894
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -'Disruption of Protein-Protein Interfaces' reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the development of useful new drugs. Consequently, in recent years great effort has been dedicated to unveiling the molecular details of protein-protein interfaces by structural techniques e.g. X-ray diffraction, NMR spectroscopy. This book, written and edited by leaders in the field, provides examples from the literature of successes and failures to develop drug-like molecules effective in interacting at protein-protein interfaces.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 172 pp. Englisch. N° de réf. du vendeur 9783642433894
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