Testosterone: Action - Deficiency - Substitution - Couverture souple

Couverture souple

ISBN 10 : 3642721877 ISBN 13 : 9783642721878

Editeur : Springer, 2011

Synopsis

The first edition of "Testosterone: Action, Deficiency, Substitu- tion" was published in 1990. Since then our understanding of the hormone that turns males into men has tremendously increased. Therefore, the editors felt that a second extended edition of the book is warranted in order to summarize established and recent findings in the field and to present the reader with an up-to-date is reflected by the textbook. The increased mass of knowledge growth of the volume from 14 to 20 chapters. In the updated edition the biochemistry and metabolism of androgens have been complemented by extensive information on the molecular biology of the androgen receptor and its disorders. The key role of testosterone in spermatogenesis is now better de- fined. We have a more complete understanding of the psychotro- pic effects of testosterone and know so much about the different target organs and functions that individual chapters deal with testosterone and the prostate, lipids and the cardiovascular sys- tem, hair, bones and muscles. The general chapter on pharmacol- ogy and clinical uses of testosterone, in particular in male hypo- gonadism, is extended by pharmacokinetic studies on testoster- one preparations and individual substitution modalities using testosterone esters as well as implants and advanced trans dermal applications. The physiologic basis and possible clinical applica- tions of testosterone in non-gonadal diseases, in male senes- cence, in hormonal male contraception and in transsexuals are discussed. The last chapter describes the role of "investigative" steroid biochemistry applied to tracking anabolic steroid abuse.

A propos du livre

Revue de presse

'... I was deeply impressed by the brilliance of selection and organization of topics, their authors, technical format and clear and instructive literary styles, which all result from the excellent editorial work ... The book certainly should be considered an important contribution to understand the contemporary knowledge about testosterone and about androgens in general.' Endocrine Regulations

'This book should be read not only by scientists dealing with steroid hormones but also by every doctor treating patients with androgen deficiency. It presents the current knowledge concerning androgen replacement therapy in a convincing manner.' Blackwell Verlag

'There is much to commend in this book ... an impressive overview.' The Endocrinologist

'This book should be read not only by scientists dealing with steroid hormones but also by every doctor treating patients with androgen deficiency. It presents the current knowledge concerning androgen replacement therapy in a convincing manner.' Andrologia

'... provides a update encyclopedia on testosterone for the years to come. the book is well edited and illustrated and concluded by a detailed index. The volume belongs in the library of all those who deal with men, both clinically and scientifically.' The Aging Male

'This is the third edition of what has become a standard reference work on all things androgenic ... there is much to commend in this book ... it remains an impressive overview of the area and the major changes made since the 1998 version are to the good.' Human Fertility

'This book is a must reference for any practitioner or researcher who is going to be involved with measuring or prescribing testosterone or, for that matter, any androgen. It is so comprehensive that urologists who consider themselves a subspecialist in either oncology, impotence, infertility or geriatrics will find the information in this tome pertinent to their subspecialty.' The Journal of Urology

Présentation de l'éditeur

This book provides information on testosterone and other androgens, and their role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behaviour, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and lipids, erection, and the prostate. Therapeutic uses of testosterone preparations are carefully evaluated, including use in women, the aging male, and its abuse and detection in sport. The book reviews applications in male contraception, the role of 5a-reductase inhibitors and the controversial use of DHEA. For this book the editors have assembled the world leaders in testosterone research and clinical andrology and endocrinology. A special feature of the book is the fact that its 24 chapters were submitted simultaneously to insure rapid publication. This revised and significantly expanded edition will serve as the standard source of reference for many years.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2011
• Langue: anglais
• ISBN 10: 3642721877
• ISBN 13: 9783642721878
• Reliure: Broché
• Numéro d'édition: 2
• Nombre de pages: 612
• Éditeur: Nieschlag Eberhard, Behre Hermann M.
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne