Articles liés à Human Melanoma: From Basic Research to Clinical Application

Human Melanoma: From Basic Research to Clinical Application - Couverture souple

 
9783642744983: Human Melanoma: From Basic Research to Clinical Application

Synopsis

Malignant melanoma is the focus of investigations which range from basic re- search to clinical trials with conventional therapy and with biological response modifiers. The involvement of investigators with different backgrounds in combi- nation with recent progress in biotechnology has facilitated the characterization of the antigenic profile of melanoma cells, the analysis of the structural and function- al properties of melanoma-associated antigens, and the application of immuno- diagnostic and immunotherapeutic approaches to melanoma. As a result, a large body of information about various aspects of melanoma has been rapidly accumu- lated during the past few years. In organizing this book I aimed at providing a readily available source of infor- mation on the current research in melanoma. To this end I invited investigators with active research programs to contribute chapters describing and discussing the significance of their most recent results. To facilitate the preparation of the manu- scripts and to avoid duplicating other recently published books on melanoma, I discouraged the contributors from providing extensive reviews of the literature on the various topics. Although I made every effort to be as complete as possible in the selection of the contributors, while writing this preface I realized that I had overlooked at least three investigators whose work should have been included.

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Présentation de l'éditeur

This is a ready source of information on melanoma, spanning from basic research to clinical investigations. Special emphasis is placed on immunology and molecular biology, and results derived from the application of biotechnology to melanoma are reviewed. Other topics discussed by leading authorities include: the characteristics of melanoma associated antigens defined by monoclonal antibodies, the role of melanoma associated antigens and HLA antigens in the biology of melanoma cells, the results of immunohistochemical studies and radio-imaging with monoclonal antibodies, and the development and application of therapeutic approaches.

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