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Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems - Couverture souple

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Ondra, Thomas

 
9783658083434: Optimized Response-Adaptive Clinical Trials: Sequential Treatment Allocation Based on Markov Decision Problems
Couverture souple
ISBN 10 : 3658083433 ISBN 13 : 9783658083434
Editeur : Springer Spektrum, 2014

Synopsis

Two-armed response-adaptive clinical trials are modelled as Markov decision problems to pursue two overriding objectives: Firstly, to identify the superior treatment at the end of the trial and, secondly, to keep the number of patients receiving the inferior treatment small. Such clinical trial designs are very important, especially for rare diseases. Thomas Ondra presents the main solution techniques for Markov decision problems and provides a detailed description how to obtain optimal allocation sequences.

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À propos de l'auteur

Thomas Ondra obtained his Master of Science degree in mathematics at University of Vienna. He is a research assistant and PhD student at the Section for Medical Statistics of Medical University of Vienna.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Springer Spektrum
Date d'édition
2014
Langue
anglais
ISBN 10 
3658083433
ISBN 13 
9783658083434
Reliure
Broché
Nombre de pages
120
Coordonnées du fabricant
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