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Tectona Grandis - A Useful Herb: Sagwan - A medicinal Plant - Couverture souple

Bhangale, Jitendra; Chaudhari, S. R.; Acharya, S. R.

 
9783659000607: Tectona Grandis - A Useful Herb: Sagwan - A medicinal Plant
Couverture souple
ISBN 10 : 3659000604 ISBN 13 : 9783659000607
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate test were used to assess antino-ciceptive activity. For evaluation of anti-inflammatory activity, carrageenan induced paw edema served as acute model. At a dose, ATG (100, 200 and 400 mg/kg, p.o.) significantly attenuated the writhing responses induced by an intraperitoneal injection of acetic acid and at ATG (200 and 400 mg/kg, p.o.) significantly increased pain latencies in tail immersion and hot plate test. In addition, the higher doses of ATG (200 and 400 mg/kg, p.o.) were inhibited carrageenan induced paw edema. From acute oral toxicity studies (OECD-423 guidelines), no mortality was observed even at highest dose of ATG (2000 mg/kg, p.o.).

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The aqueous extract of Tectona grandis bark (ATG) was investigated for anti-inflammatory and antinociceptive activity at the doses (p.o.) of 100, 200 and 400 mg/kg body weight. The acetic acid-induced writhing response, tail immersion test and hot plate test were used to assess antino-ciceptive activity. For evaluation of anti-inflammatory activity, carrageenan induced paw edema served as acute model. At a dose, ATG (100, 200 and 400 mg/kg, p.o.) significantly attenuated the writhing responses induced by an intraperitoneal injection of acetic acid and at ATG (200 and 400 mg/kg, p.o.) significantly increased pain latencies in tail immersion and hot plate test. In addition, the higher doses of ATG (200 and 400 mg/kg, p.o.) were inhibited carrageenan induced paw edema. From acute oral toxicity studies (OECD-423 guidelines), no mortality was observed even at highest dose of ATG (2000 mg/kg, p.o.).

Biographie de l'auteur

Jitendra Bhangale completed M. Pharm. DIPL from Bharati Vidyapeeth University's Poona College of Pharmacy, Pune, Maharashtra, India & currently working as Assistant Professor & Head, Department of Pharmacology, at Smt. N. M. Padalia Pharmacy College, Ahmedabad, Gujarat, India.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659000604
ISBN 13 
9783659000607
Reliure
Broché
Nombre de pages
88
Coordonnées du fabricant
non disponible
Personne responsable
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