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Studies on effects of Selenium on reproductive organs in male rats: Effects of Selenium on reproductive organs in male rats - Couverture souple

Shenoy K., Chandrakala; K.A., Nagarathna

 
9783659116162: Studies on effects of Selenium on reproductive organs in male rats: Effects of Selenium on reproductive organs in male rats
Couverture souple
ISBN 10 : 3659116165 ISBN 13 : 9783659116162
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

The present investigation was aimed to elucidate the toxic effects of selenium on male reproductive organs in albino rats by injecting sub lethal and lower doses of selenium intraperitoneally. The higher doses of selenium caused slight hypotrophy of testes and significantly decreased weights and the secretory activities of male accessory reproductive structures in male albino rats indicating that selenium might interfere with the androgen action at the target sites. It is suggested that interaction of selenium with receptor protein may change the configuration of receptor proteins, thereby decreasing the steroid binding affinity and possibly altering the way in which the receptor can interact with other cellular molecules, thus altering androgen action at the target sites. The study reveals that both low and high selenium concentrations have negative influence on reproductive performance. So dietary supplements should be used judiciously (staying well below the toxic level) and exposure to selenium should be minimized.

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À propos de l'auteur

Dr. Chandrakala Shenoy K obtained her post-graduation in Marine Biology in 1983, from Karnatak University. She did her doctoral studies in the area of Endocrinology. Currently she is working as a Professor in the Department of Biosciences, Mangalore University, India. Her area of research are Physiology and Toxicology.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659116165
ISBN 13 
9783659116162
Reliure
Broché
Nombre de pages
184
Coordonnées du fabricant
non disponible
Personne responsable
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