RD Cell Line Study of New Complexes of Some Transition Metals: Spectroscopic and Synthesis of New Complexes of Some Transition Metals - Couverture souple

Shakir, Carolin; Alias, Mahasin; Yousif, Emad

Couverture souple

ISBN 10 : 365914231X ISBN 13 : 9783659142314

Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

A new ligand of dithiocarbamato derivative containing triazole ring and hydrazide group in it, have been synthesized in this work. The product was isolated, characterized, and studied by appropriate physical measurements i.e. FT-IR, UV-Vis spectroscopy and the elemental analysis C.H.N.S as well as melting point. The new ligand was used to prepare a number of transition metal complexes (heavy and light metals). Cytotoxicity effect of some complexes (heavy metals) (PtL, AuL, RhL, CuL & PdL) as well as ligand have evaluated against RD cell line by using four different concentrations (500, 250, 125& 62.5 µg/ml) respectively, and in three exposure times 24, 48 and 72 hrs and compared this cytotoxic effect with control positive Cis-Pt, the results showed the cytotoxic effects of new compounds on RD cell line depending on both concentration and time of exposure.

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 365914231X
• ISBN 13: 9783659142314
• Reliure: Broché
• Nombre de pages: 144
• Coordonnées du fabricant: non disponible
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