Altered Thyroid State and Development of Insulin Resistance: A Correlation Study - Couverture souple

Kapadia, Kunal; Shah, Jigna; Bhatt, Parloop

 
9783659162794: Altered Thyroid State and Development of Insulin Resistance: A Correlation Study
Couverture souple
ISBN 10 : 3659162795 ISBN 13 : 9783659162794
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

The prevalence of thyroid disease in patients with diabetes is significantly higher than that in the general population.This indicates a possible interplay between thyroid status and insulin sensitivity. Complex interplay between thyroid function and insulin resistance (IR) has been implicated in diabetic dyslipidemia. Homeostatic model assessment (HOMA) of β-cell function and IR is a method for assessing β-cell function and IR from basal glucose and insulin or C-peptide concentrations. The use of HOMA to estimate insulin sensitivity and β-cell function helps to compare β-cell function and insulin sensitivity In the light of the existing reports we decided to 1) evaluate the correlation between altered thyroid state and development of IR clinically; 2) to assess β–cell function and IR by HOMA-IR. Our study concluded that thyroid disorder, including both hypo- and hyper, have been associated with IR due to various mechanism like altered insulin secretion and lipid levels. Thus even subtle increase or decrease in the thyroid levels can lead to IR leading to risk of glucose related disorder like diabetes dyslipidemia.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The prevalence of thyroid disease in patients with diabetes is significantly higher than that in the general population.This indicates a possible interplay between thyroid status and insulin sensitivity. Complex interplay between thyroid function and insulin resistance (IR) has been implicated in diabetic dyslipidemia. Homeostatic model assessment (HOMA) of β-cell function and IR is a method for assessing β-cell function and IR from basal glucose and insulin or C-peptide concentrations. The use of HOMA to estimate insulin sensitivity and β-cell function helps to compare β-cell function and insulin sensitivity In the light of the existing reports we decided to 1) evaluate the correlation between altered thyroid state and development of IR clinically; 2) to assess β–cell function and IR by HOMA-IR. Our study concluded that thyroid disorder, including both hypo- and hyper, have been associated with IR due to various mechanism like altered insulin secretion and lipid levels. Thus even subtle increase or decrease in the thyroid levels can lead to IR leading to risk of glucose related disorder like diabetes dyslipidemia.

Biographie de l'auteur

Kunal B. Kapadia, M.Pharm: Clinical Pharmacy at Gujarat Technological University, India.Junior Data Analyst: Medical Coder at Cognizant Technology Solution,India.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659162795
ISBN 13 
9783659162794
Reliure
Broché
Nombre de pages
64
Coordonnées du fabricant
non disponible
Personne responsable
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