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Metallothionin and Heavy Metals: Metallothionin: A Magic Protein - Couverture souple

Moawad Ali, Mamdouh

 
9783659183676: Metallothionin and Heavy Metals: Metallothionin: A Magic Protein
Couverture souple
ISBN 10 : 3659183679 ISBN 13 : 9783659183676
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Wide spread of pollutants present in the environment, has a profound deleterious effect on the interacellular homeostasis and may affect the gene expression. Among the most common hazards found in today's environment are the toxic metals and metalloids. Several metals have been found to produce acute and chronic tissue injury in humans and animals. It has been suggested that, one class of such toxic metals is the heavy metals as cadmium (Cd), Zinc (Zn), Copper (Cu), and Mercury (Hg). Exposure to one or more heavy metals (e.g. Cd, Cu, Ag, Zn, and Hg) had been found to elevate metallothionein concentration. The latter, was regarded as an inducible protein, and plays a key role in the homeostasis of essential metals such as Zn and Cu, and in the detoxification of some heavy metals as Cd, Hg, and Ag. When the toxic metals bound to metallothionein, they rendered inactive, and can not exert their deleterious effects on the sites of cell survival. Thus, metallothionein can help efficiently as a biochemical parameter in the diagnostic investigations for the toxicity resulted from heavy metals exposure, particularly in the industrial and polluted areas.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Wide spread of pollutants present in the environment, has a profound deleterious effect on the interacellular homeostasis and may affect the gene expression. Among the most common hazards found in today's environment are the toxic metals and metalloids. Several metals have been found to produce acute and chronic tissue injury in humans and animals. It has been suggested that, one class of such toxic metals is the heavy metals as cadmium (Cd), Zinc (Zn), Copper (Cu), and Mercury (Hg). Exposure to one or more heavy metals (e.g. Cd, Cu, Ag, Zn, and Hg) had been found to elevate metallothionein concentration. The latter, was regarded as an inducible protein, and plays a key role in the homeostasis of essential metals such as Zn and Cu, and in the detoxification of some heavy metals as Cd, Hg, and Ag. When the toxic metals bound to metallothionein, they rendered inactive, and can not exert their deleterious effects on the sites of cell survival. Thus, metallothionein can help efficiently as a biochemical parameter in the diagnostic investigations for the toxicity resulted from heavy metals exposure, particularly in the industrial and polluted areas.

Biographie de l'auteur

Prof. Dr. Mamdouh M. Ali, is Professor at the Biochemistry Dept., National Research Centre, Egypt. He published many articles in international journals. He is PI and member in several national and international projects and he is supervisor of several M.Sc. and Ph.D. students. Dr. Ali presented his researches at several international conferences.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659183679
ISBN 13 
9783659183676
Reliure
Broché
Nombre de pages
84
Coordonnées du fabricant
non disponible
Personne responsable
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