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CD4+CD25high T-Cells in Juvenile Lupus and Rheumatoid Arthritis: Quantification of CD4+CD25high T- cells in the Peripheral Blood of Children with SLE and JRA - Couverture souple

El-Ghoneimy, Dalia; Awad, Zeinab; Mostafa, Gehan

 
9783659187223: CD4+CD25high T-Cells in Juvenile Lupus and Rheumatoid Arthritis: Quantification of CD4+CD25high T- cells in the Peripheral Blood of Children with SLE and JRA
Couverture souple
ISBN 10 : 3659187224 ISBN 13 : 9783659187223
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

CD4+CD25high nTregs are the major subset of T-cells that maintain immune tolerance.Breaking self-tolerance results in autoimmunity.This book gives you a simplified review about the immune tolerance and when it is failed resulting in autoimmune diseases using SLE and JRA as examples. In addition, a chapter of possible therapeutic modalities of nTregs is included. The practial part of the book was a study of the percentages of CD4+CD25high nTregs in the peripheral blood using flowcytometry for 40 children and adolescents with pediatric SLE and JRA in addition to 20 healthy subjects as a control group. The study demonstrated the relationship of nTregs to the disease status and corticosteroids. The variation of the percentage of nTregs with the age and duration of the disease in each group was as well emphasized. At the end of the book, we drew a conclusion and recommendations for further studies in this field.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

CD4+CD25high nTregs are the major subset of T-cells that maintain immune tolerance.Breaking self-tolerance results in autoimmunity.This book gives you a simplified review about the immune tolerance and when it is failed resulting in autoimmune diseases using SLE and JRA as examples. In addition, a chapter of possible therapeutic modalities of nTregs is included. The practial part of the book was a study of the percentages of CD4+CD25high nTregs in the peripheral blood using flowcytometry for 40 children and adolescents with pediatric SLE and JRA in addition to 20 healthy subjects as a control group. The study demonstrated the relationship of nTregs to the disease status and corticosteroids. The variation of the percentage of nTregs with the age and duration of the disease in each group was as well emphasized. At the end of the book, we drew a conclusion and recommendations for further studies in this field.

Biographie de l'auteur

Dr.El-Ghoneimy is a Lecturer of Pediatrics, Pediatric Allergy and Immunology Unit, Ain Shams University, Cairo, Egypt. She is graduated from medical school in Dec 1999 with distinction and Honours and got her Master of Pediatrics in 2004 with Honours and PhD in May 2008.She has other publications in Rheumatology as well as Allergy.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659187224
ISBN 13 
9783659187223
Reliure
Broché
Nombre de pages
180
Coordonnées du fabricant
non disponible
Personne responsable
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