Characterization of CCPP in Small Ruminants: Pathogenesis and Molecular Studies on Contagious Caprine Pleuropneumonia in Goats in Khyber Pakhtunkhwa Pakistan - Couverture souple

Sadique, Umer; Chaudhry, Zafar Iqbal

 
9783659210440: Characterization of CCPP in Small Ruminants: Pathogenesis and Molecular Studies on Contagious Caprine Pleuropneumonia in Goats in Khyber Pakhtunkhwa Pakistan

Synopsis

Contagious Caprine pleuropneumonia (CCPP) is major threat to goat population world wide particularly in African countries, Middle East and subcontinent including Pakistan and Afghanistan. CCPP is caused by Mycoplasma mycoides cluster consist of six different spp having different lethal outcome. The diagnosis of this fatal disease is very difficult due to several constrains. The present study provides valuable information for the rapid and accurate diagnosis of this disease for both veterinary professional and researchers. PCR technique is more reliable and sensitive tools for diagnosis of CCPP. The Mycoplasma mycoides capri was isolated and identified from lungs tissues of infected goats. The disease was efficiently reproduced in experimental animals that adopted acute septicemic form with lethal outcomes. Immunohistochemical technique was first time optimized in Pakistan for detection of antigen within the tissues. The findings of this study will paved way for the preparation of vaccine from the field strain that would be used for effective eradication of this devastating disease from the goat population.

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À propos de l?auteur

Dr. Umer Sadique got his PhD degree from UVAS Pakistan during 2010. He is currently working as Associate Professor & Chairman Department of Animal Health Khyber Pakhtunkhwa Agricultural University Peshawar Pakistan. Prof. Dr. Zafer Iqbal Chaudhry is currently Dean Faculty of Veterinary Sciences Bahauddin Zakariya University, Multan, Pakistan.

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