New Insight On The Role Of Melatonin And Dehydroepiandrosterone - Couverture souple

Farouk Aly, Hanan; Soliman, Abdel-Mohsen; El-Sayed Mohamed, Hoda

 
9783659228414: New Insight On The Role Of Melatonin And Dehydroepiandrosterone

Synopsis

Treatment with melatonin and /or DHEA showed therapeutic effects with fluctuated ameliorative percentages in all investigated biochemical parameters ,through markedly accelerated liver regeneration after partial hepatectomy, attenuated DMN- induced liver injury by their ROS scavenging activities, modulated liver injury and liver fibrosis by inhibiting inflammatory cytokines and oxidative stress, stimulated hepatocyte mitosis, that consequently leads to the survival of rats with a high risk of postoperative liver failure after hepatectomy. These results ascertained scavenging free radicals and antioxidant activities of both drugs in enhancement regenerating liver after partial hepatectomy, DMN –induced cirrhosis and cirrhotic –partially hepatectomized liver.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Treatment with melatonin and /or DHEA showed therapeutic effects with fluctuated ameliorative percentages in all investigated biochemical parameters ,through markedly accelerated liver regeneration after partial hepatectomy, attenuated DMN- induced liver injury by their ROS scavenging activities, modulated liver injury and liver fibrosis by inhibiting inflammatory cytokines and oxidative stress, stimulated hepatocyte mitosis, that consequently leads to the survival of rats with a high risk of postoperative liver failure after hepatectomy. These results ascertained scavenging free radicals and antioxidant activities of both drugs in enhancement regenerating liver after partial hepatectomy, DMN –induced cirrhosis and cirrhotic –partially hepatectomized liver.

Biographie de l'auteur

Hanan Farouk Aly , Professor of biochemistry ,Therapeutic Chemistry Department , National Research Center , Egypt.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.