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Liposomes containing clindamycin and green tea for anti acne: Formulation and characterization of liposomes containing clindamycin and green tea for anti acne - Couverture souple

Singh, Ranjit

 
9783659277276: Liposomes containing clindamycin and green tea for anti acne: Formulation and characterization of liposomes containing clindamycin and green tea for anti acne
Couverture souple
ISBN 10 : 3659277274 ISBN 13 : 9783659277276
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Liposomes were prepared by thin film hydration method. Ten formulations of liposomes was prepared using soya lecithin, cholesterol and drug in ratios (50:50:20, 60: 40:20, 70:30; 20, 80; 20:20 and 90:10:20) respectively.The liposomes was characterized for their size, shape, encapsulation efficiency, drug content and in-vitro drug release studies. The in-vitro drug release study was done for F1 and F6 since these formulations have smaller particle size so the penetrations of drug might be increased. The formulation F1 and F6 suspension was incorporated into the gel and in-vitro drug release study was done. For this study topical liposomal gel containing 1% drugs was prepared according to the procedure and compared with the marketed non liposomal gel containing 1% clindamycin. It was found that non liposomal gel shows higher release than liposomal gel which confirmed that encapsulation of drug into liposomes, resulted in a prolonged drug release rate. Clindamycin found to be more superior against Micrococcus luteus than green tea.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Liposomes were prepared by thin film hydration method. Ten formulations of liposomes was prepared using soya lecithin, cholesterol and drug in ratios (50:50:20, 60: 40:20, 70:30; 20, 80; 20:20 and 90:10:20) respectively.The liposomes was characterized for their size, shape, encapsulation efficiency, drug content and in-vitro drug release studies. The in-vitro drug release study was done for F1 and F6 since these formulations have smaller particle size so the penetrations of drug might be increased. The formulation F1 and F6 suspension was incorporated into the gel and in-vitro drug release study was done. For this study topical liposomal gel containing 1% drugs was prepared according to the procedure and compared with the marketed non liposomal gel containing 1% clindamycin. It was found that non liposomal gel shows higher release than liposomal gel which confirmed that encapsulation of drug into liposomes, resulted in a prolonged drug release rate. Clindamycin found to be more superior against Micrococcus luteus than green tea.

Biographie de l'auteur

The author of the book Mr. Ranjit Singh was born in Meghalaya (North Eastern part of India). He completed his school life from St. Anthony's Higher Secondary School,Meghalaya. And he completed his Master degree from KMCH College of Pharmacy, Dr.M.G.R. Medical University, Tamil Nadu.The author is thankful to his parents and almighty

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659277274
ISBN 13 
9783659277276
Reliure
Broché
Nombre de pages
80
Éditeur
Sankar Chelladurai, Samuel Sandra Joji
Coordonnées du fabricant
non disponible
Personne responsable
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