Poloxamer: Introduction, Synthesis, Types & Application - Couverture souple

Patel, Dhirendra C.; Patel, Jitendra S.

 
9783659304262: Poloxamer: Introduction, Synthesis, Types & Application
Couverture souple
ISBN 10 : 3659304263 ISBN 13 : 9783659304262
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene flanked by two hydrophilic chains of polyoxyethylene. Now a day, Poloxamer are widely used in different drug delivery systems due to its biodegradability, high solubility and low toxicity. Poloxamers contain both hydrophilic and hydrophobic part, so they are used widely as surfactant and emulsifier in the formulation. Poloxamer are used in solid dispersion as solubility enhancer. Pluronic grade has thermo reversible gelation property, liquid at room temperature and convert gel at body temperature, so it is used in the control release formulation. Poloxamer are used for improve the stability of Nanoparticle and liposome. Poloxamers are used in solid suppositories for improve the dissolution of poorly soluble drugs and decrease the rectal irritation compare to conventional polymer like polyethylene glycol. Poloxamer are also used in the biological preparation as stabilizer.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene flanked by two hydrophilic chains of polyoxyethylene. Now a day, Poloxamer are widely used in different drug delivery systems due to its biodegradability, high solubility and low toxicity. Poloxamers contain both hydrophilic and hydrophobic part, so they are used widely as surfactant and emulsifier in the formulation. Poloxamer are used in solid dispersion as solubility enhancer. Pluronic grade has thermo reversible gelation property, liquid at room temperature and convert gel at body temperature, so it is used in the control release formulation. Poloxamer are used for improve the stability of Nanoparticle and liposome. Poloxamers are used in solid suppositories for improve the dissolution of poorly soluble drugs and decrease the rectal irritation compare to conventional polymer like polyethylene glycol. Poloxamer are also used in the biological preparation as stabilizer.

Biographie de l'auteur

Dhirendra C. Patel, Master of Pharmacy, Pharmaceutics at S.K. Patel College of Pharmaceutical Education and Research, Ganpat University, Kherva, Mehsana, Gujarat, India. Published International articles and books. Presented various posters. Attended various conferences. Participated in Industrial Problem Solving Ability.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3659304263
ISBN 13 
9783659304262
Reliure
Broché
Nombre de pages
64
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne