Computational methods for screening and engineering enzyme properties - Couverture souple

Knapic, Lorena

 
9783659346255: Computational methods for screening and engineering enzyme properties
Couverture souple
ISBN 10 : 365934625X ISBN 13 : 9783659346255
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute.

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Présentation de l'éditeur

Biocatalysis is an excellent alternative to classical chemical catalysis offering environmentally benign manufacturing, sustainable development and green chemistry. Understanding enzyme properties at an atomic level is the major advantage offered by computational techniques and the only route for rational engineering of enzyme properties. This work describes specifically developed state of the art methodologies that deal with enzyme reaction promiscuity and substrate promiscuity phenomena. An innovative tool for in silico enzyme evolution and screening has also been developed and its assembly from scratch and validation are thoroughly described. The existing drawbacks of industrial application of enzymes need to be overcome by a combined effort of scientists in which computational chemists and biologists have much to contribute.

Biographie de l'auteur

Dr. Lorena Knapic received her PhD form University of Trieste (Italy) in 2012. Her research was conducted in the laboratory of computational and applied biocatalysis led by prof. Lucia Gardossi. With studies done in Croatia, Italy, Sweden and Taiwan, she always aims at combining scientific excellence with a thrilling lifestyle.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
365934625X
ISBN 13 
9783659346255
Reliure
Broché
Nombre de pages
180
Coordonnées du fabricant
non disponible
Personne responsable
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