Transdermal Drug Delivery: A Challenge: Overcomming Transdermal Drug Delivery Barrier - Couverture souple

Chandra, Amrish; Srivastava, Ashish; Garg, Seema

 
9783659358807: Transdermal Drug Delivery: A Challenge: Overcomming Transdermal Drug Delivery Barrier
Couverture souple
ISBN 10 : 3659358800 ISBN 13 : 9783659358807
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

The book contains details of study carried out to evaluate the effect of various penentration enhancers (PE) on the transdermal permeation of dexamethasone. In vitro studies were performed in order to determine the optimum solvent system for the drug. The concentration of gelling agent HPMC was optimized. Further formulations were prepared and optimized for the concentration of PE to achieve maximum permeation of drug. In vitro skin permeation studies were performed using selected formulation for 24 hours, which revealed that formulation containing 5% w/w eucalyptus oil and camphor oil showed cumulative drug permeation in the desired range. Based on the observation it can be concluded that volatile oils containing terpenes are better studied over alcohols and fatty acids for increasing the permeation of dexamethasone. The formulation containing terpenes could be useful in the development of transdermal drug delivery system of dexamethasone

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The book contains details of study carried out to evaluate the effect of various penentration enhancers (PE) on the transdermal permeation of dexamethasone. In vitro studies were performed in order to determine the optimum solvent system for the drug. The concentration of gelling agent HPMC was optimized. Further formulations were prepared and optimized for the concentration of PE to achieve maximum permeation of drug. In vitro skin permeation studies were performed using selected formulation for 24 hours, which revealed that formulation containing 5% w/w eucalyptus oil and camphor oil showed cumulative drug permeation in the desired range. Based on the observation it can be concluded that volatile oils containing terpenes are better studied over alcohols and fatty acids for increasing the permeation of dexamethasone. The formulation containing terpenes could be useful in the development of transdermal drug delivery system of dexamethasone

Biographie de l'auteur

Dr. Amrish Chandra has more than 10 years of experience as faculty in Pharmaceutical Sciences. He has to his credit ten patents and many National & International publications in journals of repute. He did his graduation, post-graduation & Ph.D. in Pharmacy. His research focus in the area of transdermal & nanoparticle based drug delivery.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659358800
ISBN 13 
9783659358807
Reliure
Broché
Nombre de pages
140
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne