Antioxidant and anticancer activity of Cissus quadrangularis L. stem: Antioxidant and anticancer activity of C. quadrangularis - Couverture souple

Nagani, Krunal; Chanda, Sumitra

 
9783659364563: Antioxidant and anticancer activity of Cissus quadrangularis L. stem: Antioxidant and anticancer activity of C. quadrangularis
Couverture souple
ISBN 10 : 3659364568 ISBN 13 : 9783659364563
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

C.quadrangularis L. belongs to the family Vitaceae, an edible plant found in India. It is commonly known as “bone setter. The stems of C.quadrangularis are reported to have great medicinal value. Considering above, in the present work antioxidant, anticancer and toxicity study was evaluated. In in vitro antioxidant studies, the antioxidant activity of FS-II was better than that of ME and FS-I. FS-II showed best ABTS radical scavenging activity followed by hydroxyl radical scavenging activity, DPPH free radical scavenging activity. In anticancer studies, ME showed potent proliferation inhibitory activity against A549 and HeLa cell lines. This is the first report on the anticancer properties of C.quadrangularis. In vivo antioxidant activity revealed that FS-II of C.quadrangularis protects oxidative injury induced by CCl4 and water immersion stress. In acute toxicity study, the FS-II had no mortality andobservable acute toxic effect during the entire period in male and female rats dosed up to 800mg/kg b.w. orally.These studies have shown that the ME of C.quadrangularis and its fractions contain some active ingredients with the potential of being good antioxidant and anticancer agents.

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Présentation de l'éditeur

C.quadrangularis L. belongs to the family Vitaceae, an edible plant found in India. It is commonly known as “bone setter. The stems of C.quadrangularis are reported to have great medicinal value. Considering above, in the present work antioxidant, anticancer and toxicity study was evaluated. In in vitro antioxidant studies, the antioxidant activity of FS-II was better than that of ME and FS-I. FS-II showed best ABTS radical scavenging activity followed by hydroxyl radical scavenging activity, DPPH free radical scavenging activity. In anticancer studies, ME showed potent proliferation inhibitory activity against A549 and HeLa cell lines. This is the first report on the anticancer properties of C.quadrangularis. In vivo antioxidant activity revealed that FS-II of C.quadrangularis protects oxidative injury induced by CCl4 and water immersion stress. In acute toxicity study, the FS-II had no mortality andobservable acute toxic effect during the entire period in male and female rats dosed up to 800mg/kg b.w. orally.These studies have shown that the ME of C.quadrangularis and its fractions contain some active ingredients with the potential of being good antioxidant and anticancer agents.

Biographie de l'auteur

Dr. Krunal Nagani, Ph.D. (Biochemistry) studied in Phytochemical, Pharmacological and Microbiological Laboratory, Department of Biosciences, Saurashtra University, Rajkot 360 005, Gujarat, India.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659364568
ISBN 13 
9783659364563
Reliure
Broché
Nombre de pages
76
Coordonnées du fabricant
non disponible
Personne responsable
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