Background: Interferon gamma (IFN-γ), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines & molecules that kill MTB. IFN-γ also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-γ in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-γ conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-γ was 48.69+28.78 while it was 12.99+5.70 pg/ml in control group (p <0.001). Significant differences in the level of IFN-γ were observed among confirmed TB patients, clinically diagnosed TB patients and the control group (Mean+SD 59.68+28.78, 36.85+24.76 and 12.99+5.70 pg/ml, respectively). Furthermore, a significant negative correlation was observed b/w conc. of IFN-γ in TB patients and the duration of anti-tuberculosis therapy. Conclusion: IFN-γ level was high in both clinically diagnosed and confirmed TB patients as compared to a control group. Measurement of IFN-γ is helpful to diagnose active TB, but further research is required.
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M.Sc. in Medical Laboratory Technology: Studied immunology as subject of specialization at University of Health Sciences, Lahore. Served as Lab Manager & Teaching Research Fellow in the same University. Presently, working as Researcher (Fellow) at King Saud University, Riyadh. Future aims: career as well as education in Biomedical Sciences.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Background: Interferon gamma (IFN-¿), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines & molecules that kill MTB. IFN-¿ also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-¿ in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-¿ conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-¿ was 48.69+28.78 while it was 12.99+5.70 pg/ml in control group (p 72 pp. Englisch. N° de réf. du vendeur 9783659372407
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Hussain ShahidM.Sc. in Medical Laboratory Technology: Studied immunology as subject of specialization at University of Health Sciences, Lahore. Served as Lab Manager & Teaching Research Fellow in the same University. Presently, worki. N° de réf. du vendeur 5151861
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Taschenbuch. Etat : Neu. Neuware -Background: Interferon gamma (IFN-¿), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines & molecules that kill MTB. IFN-¿ also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-¿ in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-¿ conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-¿ was 48.69+28.78 while it was 12.99+5.70 pg/ml in control group (pBooks on Demand GmbH, Überseering 33, 22297 Hamburg 72 pp. Englisch. N° de réf. du vendeur 9783659372407
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Background: Interferon gamma (IFN-¿), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines & molecules that kill MTB. IFN-¿ also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-¿ in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-¿ conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-¿ was 48.69+28.78 while it was 12.99+5.70 pg/ml in control group (p. N° de réf. du vendeur 9783659372407
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