Robotics and Geometric Mechanics Approach to Structural Biology: For Modeling Protein Folding and Inflection Point Detection - Couverture souple

Sawlekar, Rucha; Kazi, Faruk; Singh, Navdeep M.

 
9783659372674: Robotics and Geometric Mechanics Approach to Structural Biology: For Modeling Protein Folding and Inflection Point Detection
Couverture souple
ISBN 10 : 3659372676 ISBN 13 : 9783659372674
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

The voluminous application area of Dynamics and Control as well as Systems Biology, is an upcoming and challenging research area assiduously followed by control research community. This book focuses on Protein structure prediction, Missing loop problem and Optimal alignment of two protein structures. The Missing loop problem is treated by Robotics based Inverse Kinematics (IK) method to generate the possible candidates’ ensemble for protein loop completion. Then structure prediction of proteins (namely 1YRF and 1VII) is achieved by differential geometric approach and Frenet-Quaternion frame compared with the results by nonlinear Schrödinger equation; considering the structural similarity between a protein chain and a robotic arm. The results clearly show the location of inflection points that distinctly determine helix-loop-helix structure of the protein under study. Also, Quaternion based optimal alignment of two protein structures is performed and compared with the results by Kabsch method.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The voluminous application area of Dynamics and Control as well as Systems Biology, is an upcoming and challenging research area assiduously followed by control research community. This book focuses on Protein structure prediction, Missing loop problem and Optimal alignment of two protein structures. The Missing loop problem is treated by Robotics based Inverse Kinematics (IK) method to generate the possible candidates’ ensemble for protein loop completion. Then structure prediction of proteins (namely 1YRF and 1VII) is achieved by differential geometric approach and Frenet-Quaternion frame compared with the results by nonlinear Schrödinger equation; considering the structural similarity between a protein chain and a robotic arm. The results clearly show the location of inflection points that distinctly determine helix-loop-helix structure of the protein under study. Also, Quaternion based optimal alignment of two protein structures is performed and compared with the results by Kabsch method.

Biographie de l'auteur

Rucha Sawlekar received her Masters’ degree in Electrical Engineering with specialization in Control Systems from VJTI, Mumbai University in 2012 and worked with the same institute as an Assistant Professor. Her research interests are in Dynamics and Control, Robotics, Protein Dynamics and Systems Biology.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659372676
ISBN 13 
9783659372674
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne