Protein Structure Prediction based on Evolutionary Methods - Couverture souple

Márquez Chamorro, Alfonso E.

 
9783659393488: Protein Structure Prediction based on Evolutionary Methods
Couverture souple
ISBN 10 : 3659393487 ISBN 13 : 9783659393488
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

The problem of Protein Structure Prediction (PSP) is one of the principal topics in Bioinformatics. Multiple approaches have been developed in order to predict the protein structure of a protein. Determining the three dimensional structure of proteins is necessary to understand the functions of molecular protein level. An useful, and commonly used, representation for protein 3D structure is the protein contact map, which represents binary proximities (contact or non-contact) between each pair of amino acids of a protein. This book includes a compilation of the soft computing techniques for the protein structure prediction problem (secondary and tertiary structures). Two novel evolutionary structure predictors are also described in this work: a multi-objective evolutionary approach for contact map prediction and an evolutionary secondary structure predictor. Both of them are based on physico-chemical properties of amino acids. The evolutionary algorithms produce a set of decision rules that identifies contacts between amino acids and secondary structure motifs, respectively. Results obtained confirm the validity of our proposals.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The problem of Protein Structure Prediction (PSP) is one of the principal topics in Bioinformatics. Multiple approaches have been developed in order to predict the protein structure of a protein. Determining the three dimensional structure of proteins is necessary to understand the functions of molecular protein level. An useful, and commonly used, representation for protein 3D structure is the protein contact map, which represents binary proximities (contact or non-contact) between each pair of amino acids of a protein. This book includes a compilation of the soft computing techniques for the protein structure prediction problem (secondary and tertiary structures). Two novel evolutionary structure predictors are also described in this work: a multi-objective evolutionary approach for contact map prediction and an evolutionary secondary structure predictor. Both of them are based on physico-chemical properties of amino acids. The evolutionary algorithms produce a set of decision rules that identifies contacts between amino acids and secondary structure motifs, respectively. Results obtained confirm the validity of our proposals.

Biographie de l'auteur

Dr. Alfonso E. Márquez Chamorro received the degree and the MS degree in Computer Science from the Autónoma University of Madrid, in 2007 and 2009. In 2013, he obtained his PhD degree in Biotechnology from the Pablo de Olavide University of Seville. His research interests focus mainly on Machine Learning and Data Mining applied to Bioinformatics.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659393487
ISBN 13 
9783659393488
Reliure
Broché
Nombre de pages
204
Coordonnées du fabricant
non disponible
Personne responsable
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