Development of Self Microemulsifying Drug Delivery System: Design and Development of Self Microemulsifying Drug Delivery System of Clopidogrel Bisulphate - Couverture souple

Patel, Priyank B.; Patel, Mukesh R.

 
9783659404795: Development of Self Microemulsifying Drug Delivery System: Design and Development of Self Microemulsifying Drug Delivery System of Clopidogrel Bisulphate
Couverture souple
ISBN 10 : 3659404799 ISBN 13 : 9783659404795
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils, surfactant dispersions, self-emulsifying formulations, emulsions and liposomes with particular emphasis on self microemulsifying drug delivery systems (SMEDDS).

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Présentation de l'éditeur

Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate. . In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drug compounds. In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils, surfactant dispersions, self-emulsifying formulations, emulsions and liposomes with particular emphasis on self microemulsifying drug delivery systems (SMEDDS).

Biographie de l'auteur

Priyank B. Patel(P.G.student), Dr. Mukesh R. Patel(head of Department of Pharmaceutics),Shri B.M.Shah College of Pharmaceutical Education and Research, Modasa-383315, India

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659404799
ISBN 13 
9783659404795
Reliure
Broché
Nombre de pages
108
Coordonnées du fabricant
non disponible
Personne responsable
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Autres éditions populaires du même titre

9783844331820: Development of Self Microemulsifying Drug Delivery System: Preparation and evaluation of Lovastatin Self Microemulsifying Drug Delivery System

Edition présentée

ISBN 10 :  3844331824 ISBN 13 :  9783844331820
Editeur : LAP LAMBERT Academic Publishing, 2011
Couverture souple