Formulation Development of Extended Released Rifaximin Micro-particles - Couverture souple

Bhise Kiran; Karanje Rohan

 
9783659418402: Formulation Development of Extended Released Rifaximin Micro-particles
Couverture souple
ISBN 10 : 3659418404 ISBN 13 : 9783659418402
Editeur : LAP Lambert Academic Publishing, 2015

Synopsis

This book addresses the formulation and process design aspects of extended release micro particles of BCS class IV drug Rifaximin through cyclodextrin complexation and extending the drug release by Eudragit L -100 enteric coating. The concept of surface response methodology was used in the selection of optimized batch that was further evaluated for various parameters. The data supports an improvement in aqueous solubility of BCS class IV drugs through cyclodextrin complexes. The release of such inclusion complexes can be retarded for 8 hrs by enteric coating.

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Éditeur
LAP Lambert Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659418404
ISBN 13 
9783659418402
Reliure
Broché
Nombre de pages
128
Coordonnées du fabricant
non disponible
Personne responsable
non disponible