Articles liés à Drugs' Enantioresolution-Why and How?-Liquid Chromatogra...

Drugs' Enantioresolution-Why and How?-Liquid Chromatographic Approach: Recent Application of Drugs' Enantioresolution - Couverture souple

Dubey, Rituraj

 
9783659420887: Drugs' Enantioresolution-Why and How?-Liquid Chromatographic Approach: Recent Application of Drugs' Enantioresolution
Couverture souple
ISBN 10 : 3659420883 ISBN 13 : 9783659420887
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

Drugs’ enantioresolution is one of the emerging areas as the enantiomers of a chiral drugs have different pharmacological effects as only one enantiomer of the drug often exhibits the desirable therapeutic activity, while the other shows an antagonistic function, side effects, or even toxic effects. These properties of the enantiomers have created an interest to study the pharmacological and toxicological behaviors of the individual enantiomers of drugs, pharmaceuticals, and agrochemicals. The United States Food and Drug Administration has issued guidelines to pharmaceutical and agrochemical industries to specify the enantiomeric purity of the optically active compounds prior to their marketing and hence demanded a systematic investigation of the biological behavior of their individual enantiomers and significantly encouraged the development of single enantiomer drugs. In view of these facts, the enantioresolution of a variety of drugs is gaining importance continuously.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Drugs’ enantioresolution is one of the emerging areas as the enantiomers of a chiral drugs have different pharmacological effects as only one enantiomer of the drug often exhibits the desirable therapeutic activity, while the other shows an antagonistic function, side effects, or even toxic effects. These properties of the enantiomers have created an interest to study the pharmacological and toxicological behaviors of the individual enantiomers of drugs, pharmaceuticals, and agrochemicals. The United States Food and Drug Administration has issued guidelines to pharmaceutical and agrochemical industries to specify the enantiomeric purity of the optically active compounds prior to their marketing and hence demanded a systematic investigation of the biological behavior of their individual enantiomers and significantly encouraged the development of single enantiomer drugs. In view of these facts, the enantioresolution of a variety of drugs is gaining importance continuously.

Biographie de l'auteur

Dr. Rituraj Dubey has accomplished his Ph.D.(Chemistry) from Indian Institute of Technology Roorkee, India. He is currently working as NSC Post-doctoral Fellow in Department of Chemistry, National Cheng Kung University, Taiwan in the field of biochemical probes, soft-material based bio-chips, proteomics study related to estogen action using LC-MS.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659420883
ISBN 13 
9783659420887
Reliure
Broché
Nombre de pages
188
Coordonnées du fabricant
non disponible
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