Formulation of loxoprofen loaded-microspheres: Optimization using chemometric protocol - Couverture souple

Venkatesan, Palanivel ; Valliappan, Kannappan

9783659436376: Formulation of loxoprofen loaded-microspheres: Optimization using chemometric protocol

Couverture souple

ISBN 10 : 3659436372 ISBN 13 : 9783659436376

Editeur : LAP LAMBERT Academic Publishing, 2013

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Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres.

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� propos de l?auteur

Dr.P.Venkatesan is working as Assistant professor, Department of Pharmacy, Annamalai University,India. His research interest is in the design, development and optimization of NDDS. He has a number of research publications in peer reviewed journals of repute to his credit. Dr. Venkatesan is the Deputy Coordinator of the UGC SAP DRS Phase-l Project.

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: LAP LAMBERT Academic Publishing
Date d'�dition: 2013
Langue: anglais
ISBN 10: 3659436372
ISBN 13: 9783659436376
Reliure: Broch�
Nombre de pages: 220
Coordonn�es du fabricant: non disponible
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Formulation of loxoprofen loaded-microspheres

Palanivel Venkatesan

Edit� par LAP LAMBERT Academic Publishing Sep 2013, 2013

ISBN 10 : 3659436372 ISBN 13 : 9783659436376

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres. 220 pp. Englisch. N� de r�f. du vendeur 9783659436376

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Formulation of loxoprofen loaded-microspheres

Palanivel Venkatesan|Kannappan Valliappan

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Venkatesan PalanivelDr.P.Venkatesan is working as Assistant professor, Department of Pharmacy, Annamalai University,India. His research interest is in the design, development and optimization of NDDS. He has a number of research publ. N� de r�f. du vendeur 5156128

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Formulation of loxoprofen loaded-microspheres | Optimization using chemometric protocol

Palanivel Venkatesan (u. a.)

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ISBN 10 : 3659436372 ISBN 13 : 9783659436376

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Formulation of loxoprofen loaded-microspheres

Palanivel Venkatesan

Edit� par LAP LAMBERT Academic Publishing Sep 2013, 2013

ISBN 10 : 3659436372 ISBN 13 : 9783659436376

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres.VDM Verlag, Dudweiler Landstra�e 99, 66123 Saarbr�cken 220 pp. Englisch. N� de r�f. du vendeur 9783659436376

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Formulation of loxoprofen loaded-microspheres : Optimization using chemometric protocol

Palanivel Venkatesan

Edit� par LAP LAMBERT Academic Publishing, 2013

ISBN 10 : 3659436372 ISBN 13 : 9783659436376

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Sustained release formulations often face the challenge of finding the right combination of formulation variables that will produce a product with optimum properties. Optimization becomes even more important when the formulation is a sustained-release dosage form, since many often-interdependent factors can affect the release rate. In this study, we have investigated the effect of formulation variables on several responses. Subsequently, response surface methodology was applied to optimize the formulation after constructing a desirability function that simultaneously combines all the four responses. Formulations of loxoprofen-loaded sustained release microspheres were prepared by solvent evaporation technique and optimized using response surface methodology by fitting a second-order model to the response data. This book provides a detailed discussion on chemometric procedure for the optimization of formulation variables, development of regression models and global optimization of response variables to design quality formulation. This work could form a reference material to those aspiring to pursue research in the design, development and optimization of microspheres. N� de r�f. du vendeur 9783659436376

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