Isodon coetsa: Genotoxic consequences & essential oil profile - Couverture souple

Neelamkavil, Sandhya Vincent; Thoppil, John E.

 
9783659452895: Isodon coetsa: Genotoxic consequences & essential oil profile
Couverture souple
ISBN 10 : 3659452890 ISBN 13 : 9783659452895
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

Isodon (Schrad. ex Benth.) Spach is a cosmopolitan and important genus of Lamiaceae family and many of its species are used in folk medicine. About 150 species of undershrubs, subundershrubs or perennial herbs are found throughout the world mainly in tropical and subtropical Asia. Many plants of this genus are used in the treatment of respiratory and gastrointestinal bacterial infections, enteritis, jaundice and pneumonia. It is also hepatoprotective in activity. Isodon diterpenoids have attracted considerable attention as antibacterial, antitumor, anti inflammatory, antimalarial and antifeeding agents. A number of isolated diterpenoids have been found to have potent antitumor activities with low toxicity. The study deals with the cytotoxic activities of aqueous leaf extracts of Isodon coetsa. The activity was analysed for both polar & nonpolar components & polar components alone. Highest activity was reported for extracts with both polar & nonpolar components. Essential oil analysis was thus conducted using gas chromatography mass spectrometry. This resulted in construction of an essential oil profile along with genotoxic reports.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Isodon (Schrad. ex Benth.) Spach is a cosmopolitan and important genus of Lamiaceae family and many of its species are used in folk medicine. About 150 species of undershrubs, subundershrubs or perennial herbs are found throughout the world mainly in tropical and subtropical Asia. Many plants of this genus are used in the treatment of respiratory and gastrointestinal bacterial infections, enteritis, jaundice and pneumonia. It is also hepatoprotective in activity. Isodon diterpenoids have attracted considerable attention as antibacterial, antitumor, anti inflammatory, antimalarial and antifeeding agents. A number of isolated diterpenoids have been found to have potent antitumor activities with low toxicity. The study deals with the cytotoxic activities of aqueous leaf extracts of Isodon coetsa. The activity was analysed for both polar & nonpolar components & polar components alone. Highest activity was reported for extracts with both polar & nonpolar components. Essential oil analysis was thus conducted using gas chromatography mass spectrometry. This resulted in construction of an essential oil profile along with genotoxic reports.

Biographie de l'auteur

Sandhya Vincent Neelamkavil M Phil, is a research scholar of Dr John E Thoppil, Associate Professor, Cell & Molecular Biology Division, Department of Botany, University of Calicut. Field of interest-Cell Biology(Chromosome Imaging, Karyomorphometry, Cytotoxicity), Molecular Biology(RAPD, Gene Sequencing) & Essential Oil Research(Bioactivity, GC-MS)

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659452890
ISBN 13 
9783659452895
Reliure
Broché
Nombre de pages
152
Coordonnées du fabricant
non disponible
Personne responsable
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