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Genetic Identification of Second World War Victim's Skeletal Remains - Couverture souple

Zupanič Pajnič, Irena

 
9783659453069: Genetic Identification of Second World War Victim's Skeletal Remains
Couverture souple
ISBN 10 : 3659453064 ISBN 13 : 9783659453069
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

This book describes genetics investigations of DNA from a Second World War victim’s skeletal remains and their genetic identification. The characteristics of ancient DNA and the environmental factors that affect its preservation are described. The recommendations for excavation, storage and molecular genetic identification of skeletal remains are presented. The method of how reference samples from relatives and samples for the elimination database are collected and analysed for each mass grave is shown. The most appropriate types of bones and teeth for genetic analyses are described and the measures for preventing contamination in the DNA laboratory are listed. Procedures for processing the bone sample (mechanical and chemical cleaning, cutting and grinding into powder), decalcification of bone powder, DNA extraction, DNA quantification and DNA typing of autosomal and Y chromosomal microsatellites and mitochondrial DNA are described and interpretation of genetic profiles with statistical calculations of the likelihood ratio and posterior probability are exposed. Some examples of identification of the Second World War mass grave victims are presented.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This book describes genetics investigations of DNA from a Second World War victim’s skeletal remains and their genetic identification. The characteristics of ancient DNA and the environmental factors that affect its preservation are described. The recommendations for excavation, storage and molecular genetic identification of skeletal remains are presented. The method of how reference samples from relatives and samples for the elimination database are collected and analysed for each mass grave is shown. The most appropriate types of bones and teeth for genetic analyses are described and the measures for preventing contamination in the DNA laboratory are listed. Procedures for processing the bone sample (mechanical and chemical cleaning, cutting and grinding into powder), decalcification of bone powder, DNA extraction, DNA quantification and DNA typing of autosomal and Y chromosomal microsatellites and mitochondrial DNA are described and interpretation of genetic profiles with statistical calculations of the likelihood ratio and posterior probability are exposed. Some examples of identification of the Second World War mass grave victims are presented.

Biographie de l'auteur

Irena Zupanič Pajnič, PhD in Genetics. Studied Biology at the University of Ljubljana. Assist. prof. and Senior Research Collaborator at Univerity of Ljubljana. Head of Laboratory Operations at the Laboratory of Molecular Genetics of the Institute of Forensic Medicine, Faculty of Medicine, University of Ljubljana, Slovenia

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659453064
ISBN 13 
9783659453069
Reliure
Broché
Nombre de pages
88
Coordonnées du fabricant
non disponible
Personne responsable
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