Articles liés à Bioprocess Techniques in Protein Purification: Purification...

Bioprocess Techniques in Protein Purification: Purification of Recombinant Bovine Serum Albumin from E-Coli Fermented Broth - Couverture souple

Raju, Eldho

 
9783659481017: Bioprocess Techniques in Protein Purification: Purification of Recombinant Bovine Serum Albumin from E-Coli Fermented Broth
Couverture souple
ISBN 10 : 3659481017 ISBN 13 : 9783659481017
Editeur : LAP LAMBERT Academic Publishing, 2013

Synopsis

In recent years, there has been a mounting concern over the use of animal products in many pharmaceutical and biotech industry applications because of the threat of animal viruses and transmissible sponge-form ensephelopathies, that may be present in bovine-derived proteins. Current methods of preparation involve purification of the protein from bovine plasma and testing for the presence of these contaminating agents. However, testing can only detect known viruses or TSEs and does not uncover infectious agents that have not yet been discovered. Therefore, there is currently no alternative large-scale supply of BSA that is assured to be free of all animal-derived infectious agents. So we want to optimize a method for BSA purification in small scale which is scalable. The source of the protein is from recombinant production.Purification of recombinant BSA produced from fermentation involves extraction, primary, secondary purification and polishing steps. Different techniques applied in purification of proteins based on their molecular properties.

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Présentation de l'éditeur

In recent years, there has been a mounting concern over the use of animal products in many pharmaceutical and biotech industry applications because of the threat of animal viruses and transmissible sponge-form ensephelopathies, that may be present in bovine-derived proteins. Current methods of preparation involve purification of the protein from bovine plasma and testing for the presence of these contaminating agents. However, testing can only detect known viruses or TSEs and does not uncover infectious agents that have not yet been discovered. Therefore, there is currently no alternative large-scale supply of BSA that is assured to be free of all animal-derived infectious agents. So we want to optimize a method for BSA purification in small scale which is scalable. The source of the protein is from recombinant production.Purification of recombinant BSA produced from fermentation involves extraction, primary, secondary purification and polishing steps. Different techniques applied in purification of proteins based on their molecular properties.

Biographie de l'auteur

Working as research scientist in US Pharma Lab, USA. Completed engineering in Biotechnology from Anna University. Did MS in pharmaceutical engineering from NJIT,USA and completed MS in Biotechnology from KEAN University,USA. Finished research in drug discovery and development using LC-MS at Kean University and got award for research presentation.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2013
Langue
anglais
ISBN 10 
3659481017
ISBN 13 
9783659481017
Reliure
Broché
Nombre de pages
92
Coordonnées du fabricant
non disponible
Personne responsable
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