Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools - Couverture souple

Sugapriya Menaga, Paulraj

Couverture souple

ISBN 10 : 3659513857 ISBN 13 : 9783659513855

Editeur : LAP Lambert Academic Publishing, 2014

Synopsis

KATP Channels couple glucose metabolism to membrane potential and thus play a central role in glucose stimulated insulin secretion. Genetic mutations in the genes encoding the channel subunits (Kir 6.2) can cause Congenital Hyperinsulinism (CHI). BLAST and FASTA similarity searches reveals the closely relatedness of Kir6.2 with other inwardly rectifying K+ channel family of proteins. The phylogenetic analysis showed the evolutionary relationship of various mammals with reference to Kir6.2. The secondary structure prediction, Tranmembrane and hydropathy prediction reveals the Kir6.2 contained more number of helical regions.Further, the Kir6.2 protein contains motifs which are responsible for Prokaryotic membrane lipoprotein lipid attachment site, cAMP and cGMP dependent protein kinase, casein kinase II and Protein Kinase C phosphorylation site.

A propos du livre

À propos de l?auteur

Sugapriyamenaga Paulraj is having 9 years of teaching experience and currently working as Assistant Professor in Biotechnology, ANJAC, Sivakasi. She completed UG Biochemistry, PG Integrated Biology, ADBI, PGDCA & MPhil in Biotech.Received two TNSCST Projects & guided 20 M.Sc. student Projects. The Author is having good knowledge in Bioinformatics.

Détails de l'édition

• Éditeur: LAP Lambert Academic Publishing
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 3659513857
• ISBN 13: 9783659513855
• Reliure: Broché
• Nombre de pages: 104
• Coordonnées du fabricant: non disponible
• Personne responsable: KreGa Onlinehandel GmbH; 4950000000000; info@krega-onlinehandel.de; ; Birkenweg 31; Brakel; 33034; Allemagne