Articles liés à Some Ni(II)Complexes; Design and Biological activity...

Some Ni(II)Complexes; Design and Biological activity Evaluation: Synthesis,Characterization, DNA-Interaction and anti-Microbial activity evaluation of some Ni(II) complexes - Couverture souple

Abdo Mahmoud, Ali; Rabia, Mostafa K.; M. Mohamad, Ahmad Desoky

 
9783659518225: Some Ni(II)Complexes; Design and Biological activity Evaluation: Synthesis,Characterization, DNA-Interaction and anti-Microbial activity evaluation of some Ni(II) complexes
Couverture souple
ISBN 10 : 3659518220 ISBN 13 : 9783659518225
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

Today Coordination Chemistry comprises a large body of Inorganic Chemistry research; it has fascinated and inspired the chemists all over the world. There is an ever increasing academic, commercial and biochemical interest on the metal complexes of organic chelating ligands. This has resulted in the emergence of applied fields like Organometalic Chemistry, Homogeneous Catalysis and Bioinorganic Chemistry. Between all of the chelating ligands, Isatin-hydrazone Ligands have attracted the attention of Chemists due to the ease of preparation and complexation.So, it Is important to create novel isatin derivatives for emerging drug targets. In this work we aim to design some Ni(II) complexes with newly synthesized Isatin-bishydrazones ligands, Testing their in-vitro antibacterial and antifungal activity against many types of bacteria and anti fungal cultures, which are common contaminants of the environment in Egypt,and also investigate their interaction with (CT-DNA) using UV–visible spectroscopy, and hydrodynamic technique under physiological conditions (at stomach (4.7) and blood (7.4) pH and at body temperature (37 0C) ).

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Today Coordination Chemistry comprises a large body of Inorganic Chemistry research; it has fascinated and inspired the chemists all over the world. There is an ever increasing academic, commercial and biochemical interest on the metal complexes of organic chelating ligands. This has resulted in the emergence of applied fields like Organometalic Chemistry, Homogeneous Catalysis and Bioinorganic Chemistry. Between all of the chelating ligands, Isatin-hydrazone Ligands have attracted the attention of Chemists due to the ease of preparation and complexation.So, it Is important to create novel isatin derivatives for emerging drug targets. In this work we aim to design some Ni(II) complexes with newly synthesized Isatin-bishydrazones ligands, Testing their in-vitro antibacterial and antifungal activity against many types of bacteria and anti fungal cultures, which are common contaminants of the environment in Egypt,and also investigate their interaction with (CT-DNA) using UV–visible spectroscopy, and hydrodynamic technique under physiological conditions (at stomach (4.7) and blood (7.4) pH and at body temperature (37 0C) ).

Biographie de l'auteur

Born in January 18th,1989,got his B.Sc degree in chemistry with degree of honors in 2010.Working as Teaching assistant at chemistry department,Faculty of Science,Sohag University,Egypt.His research interests in Synthesis,Characterization,Biological Evaluation,Kinetics and Spectroscopic Studies of important Bio-active Organic and Inorganic Compounds.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
3659518220
ISBN 13 
9783659518225
Reliure
Broché
Nombre de pages
140
Coordonnées du fabricant
non disponible
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