Development and optimization of naproxen sustained release tablets: Using Surface response methodology - Couverture souple

Azharuddin, Md; Umesh Rao, Vinay

 
9783659521225: Development and optimization of naproxen sustained release tablets: Using Surface response methodology

Synopsis

Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic, systemic inflammatory disorder that may affect many tissues and organs. It can be a disabling and painful condition, which can lead to substantial loss of functioning and mobility if not adequately treated. Naproxen is effective for the usual rheumatologic indications. But, the drug is practically insoluble at low pH and freely soluble at high pH. So, the drug release was controlled by formulating it into a sustained release matrix system with the help of hydrophilic polymers. The current work focuses on the development and optimization of Naproxen 800mg tablets using surface response methodology. This work will be useful to those research scholars who are willing to their research on sustained release tablets using Factorial design.

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Présentation de l'éditeur

Rheumatoid arthritis (RA) is an autoimmune disease that results in a chronic, systemic inflammatory disorder that may affect many tissues and organs. It can be a disabling and painful condition, which can lead to substantial loss of functioning and mobility if not adequately treated. Naproxen is effective for the usual rheumatologic indications. But, the drug is practically insoluble at low pH and freely soluble at high pH. So, the drug release was controlled by formulating it into a sustained release matrix system with the help of hydrophilic polymers. The current work focuses on the development and optimization of Naproxen 800mg tablets using surface response methodology. This work will be useful to those research scholars who are willing to their research on sustained release tablets using Factorial design.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Autres éditions populaires du même titre

9786208892302: Development and optimization of naproxen sustained release tablets

Edition présentée

ISBN 10 :  6208892309 ISBN 13 :  9786208892302
Editeur : LAP Lambert Academic Publishing, 2025
Couverture souple