Non-Coding Repetitive DNA Sequences: Biological Role - Couverture souple

Kahsay, Abraha Gebregziabher

 
9783659536823: Non-Coding Repetitive DNA Sequences: Biological Role

Synopsis

In recent years, non-coding DNA sequence has attracted a lot of attention of researchers. This has been mainly due to the realization that a large fraction in some cases the majority of functional DNA in human and other genomes is not encoded by protein-coding sequences but by other sequences, the exact function of which remains elusive. There are clear theoretical reasons and many well documented examples which show that non-coding repetitive DNA is essential for genome function. Generic repeated signals in the DNA are necessary to format expression of unique coding sequence files and to organize additional functions essential for genome replication and accurate transmission to progeny cells. Repetitive DNA sequence elements are also fundamental to the cooperative molecular interactions forming nucleoprotein complexes.

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Présentation de l'éditeur

In recent years, non-coding DNA sequence has attracted a lot of attention of researchers. This has been mainly due to the realization that a large fraction in some cases the majority of functional DNA in human and other genomes is not encoded by protein-coding sequences but by other sequences, the exact function of which remains elusive. There are clear theoretical reasons and many well documented examples which show that non-coding repetitive DNA is essential for genome function. Generic repeated signals in the DNA are necessary to format expression of unique coding sequence files and to organize additional functions essential for genome replication and accurate transmission to progeny cells. Repetitive DNA sequence elements are also fundamental to the cooperative molecular interactions forming nucleoprotein complexes.

Biographie de l'auteur

Dr. Abraha Gebregziabher Kahsay(DVM, MSc, Assistant professor). He has studied DVM degree at Addis Ababa University, Ethiopia, MSc in Molecular Biology and Biochemistry at Northeast Normal University, China, MSc in Epidemiology at Institute of Tropical Medicine and he has been working at Wollo University, Ethiopia as a Lecturer and Researcher.

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