Articles liés à Rational Drug Design of Substituted Analogues Angiotensin...

Rational Drug Design of Substituted Analogues Angiotensin II Receptor: Statistical approach QSAR for group-specific biological Activity Predictions;Different Series of Substituted Analogues - Couverture souple

Sharma, Mukesh C.; Sharma, Smita

 
9783659542961: Rational Drug Design of Substituted Analogues Angiotensin II Receptor: Statistical approach QSAR for group-specific biological Activity Predictions;Different Series of Substituted Analogues
Couverture souple
ISBN 10 : 3659542962 ISBN 13 : 9783659542961
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

Hypertension has become one of the most important preventable causes for premature morbidity and mortality worldwide. To identify novel and potent antihypertensive ligands, initially 2D-QSAR, Group based QSAR, kNN based 3D-QSAR and pharmacophore were generated using namely, a series of triazolinone, quinazolinone, and benzimidazole derivatives of as Angiotensin II AT1 Receptor. In conclusion, the models developed to predict the structural features of substituted analogues angiotensin II receptor antagonists, reveals useful information about the structural features requirement for the molecule.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Hypertension has become one of the most important preventable causes for premature morbidity and mortality worldwide. To identify novel and potent antihypertensive ligands, initially 2D-QSAR, Group based QSAR, kNN based 3D-QSAR and pharmacophore were generated using namely, a series of triazolinone, quinazolinone, and benzimidazole derivatives of as Angiotensin II AT1 Receptor. In conclusion, the models developed to predict the structural features of substituted analogues angiotensin II receptor antagonists, reveals useful information about the structural features requirement for the molecule.

Biographie de l'auteur

Dr Mukesh C. Sharma working as Assistant Professor in School of Pharmacy Devi Ahilya Vishwavidylaya Indore. Dr Mukesh C. Sharma and Dr Smita Sharma Research area of interest includes molecular modeling, In silico Drug Designing, Synthetic Chemistry. He has published various research papers in reputed International Journals.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
3659542962
ISBN 13 
9783659542961
Reliure
Broché
Nombre de pages
100
Coordonnées du fabricant
non disponible
Personne responsable
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