Click Chemistry and Applications: Alkynes and Azides Cu(I) Catalyzed Cycloaddition Reaction - Couverture souple

El-Azab, Adel S.; Abdel-Aziz, Alaa A.-M.

 
9783659555466: Click Chemistry and Applications: Alkynes and Azides Cu(I) Catalyzed Cycloaddition Reaction
Couverture souple
ISBN 10 : 3659555460 ISBN 13 : 9783659555466
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

Click Chemistry ‘CC’ are Cu(I) catalyzed 1,3-dipolar [3+2] cycloaddition between azides and alkynes [CuAAC]. The versatility of CuAAC or ‘click reaction’ seem endless with the discovery and invention of new chemical transformations which meet ‘click’ status, the future looks bright for CC. Recently, Click chemistry has received considerable attention as powerful modular synthesis approach, which has found numerous applications in many areas of modern organic chemistry, drug discovery, radiopharmaceutical sciences and material science. The great success of CC encouraged researchers to develop alternative “spring-loaded” chemical reactions for use in different fields of chemistry. Initially, CuAAC was the only click reaction. In recent years, metal-free [3+2] cycloaddition reactions, Diels–Alder reactions, and thiol-alkene radical addition reactions have come to the fore as click reactions because of their simple synthetic procedures and high yields. Also, these metal-free reactions have wide applicability and are physiologically compatible. Alternative CC expand the opportunities for synthesizing small organic compounds well as tailor-made macromolecules and bioconjugates.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Click Chemistry ‘CC’ are Cu(I) catalyzed 1,3-dipolar [3+2] cycloaddition between azides and alkynes [CuAAC]. The versatility of CuAAC or ‘click reaction’ seem endless with the discovery and invention of new chemical transformations which meet ‘click’ status, the future looks bright for CC. Recently, Click chemistry has received considerable attention as powerful modular synthesis approach, which has found numerous applications in many areas of modern organic chemistry, drug discovery, radiopharmaceutical sciences and material science. The great success of CC encouraged researchers to develop alternative “spring-loaded” chemical reactions for use in different fields of chemistry. Initially, CuAAC was the only click reaction. In recent years, metal-free [3+2] cycloaddition reactions, Diels–Alder reactions, and thiol-alkene radical addition reactions have come to the fore as click reactions because of their simple synthetic procedures and high yields. Also, these metal-free reactions have wide applicability and are physiologically compatible. Alternative CC expand the opportunities for synthesizing small organic compounds well as tailor-made macromolecules and bioconjugates.

Biographie de l'auteur

Adel S. El-Azab and Alaa A.-M. Abdel-Aziz, awarded Ph.D. in organic Chemistry in 2001 from Tohoku and Kumamoto Universities, Japan. They are working as Professor at the College of Pharmacy, Al-Azhar and Mansoura Universities, Egypt. Currently, work as staff members at College of Pharmacy, King Saud University, Saudi Arabia

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
3659555460
ISBN 13 
9783659555466
Reliure
Broché
Nombre de pages
152
Coordonnées du fabricant
non disponible
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