Impact of Almond oil on endothelial dysfunction in diabetic rats - Couverture souple

Anwar, Mona; A. El-bana, Mona; Awadallah, Raafat

 
9783659573521: Impact of Almond oil on endothelial dysfunction in diabetic rats
Couverture souple
ISBN 10 : 3659573523 ISBN 13 : 9783659573521
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

The present study was designed to evaluate the efficacy of almond oil and diosmin extracted from lemon peels on the endothelial dysfunction in streptozotocin induced diabetic rats. The study was performed on 75 male white albino rats divided into 5 groups. Healthy rats served as control group, diabetic group, almond oil treated diabetic group, dimethylsulfoxide treated diabetic group, and diosmin treated diabetic group. Experimental diabetes was induced by single subcutaneous injection of 50mg/kg body weight streptozotocin. After two months blood samples were collected for assessment of serum triglycerides, total, high density lipoprotein, and low density lipoprotein cholesterol, fasting blood sugar, serum insulin, intercellular adhesion molecule-1, nitrite and nitrate, plasma hydrogen peroxide, glutathione peroxidase activity and percent of DNA damage. The result showed that supplementation with almond oil and diosmin exerted an anti atherogenic effect with amelioration of glycemic status along with decreased DNA damage in STZ induced diabetic rats, these effects are more pronounced in diabetic group treated almond oil.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The present study was designed to evaluate the efficacy of almond oil and diosmin extracted from lemon peels on the endothelial dysfunction in streptozotocin induced diabetic rats. The study was performed on 75 male white albino rats divided into 5 groups. Healthy rats served as control group, diabetic group, almond oil treated diabetic group, dimethylsulfoxide treated diabetic group, and diosmin treated diabetic group. Experimental diabetes was induced by single subcutaneous injection of 50mg/kg body weight streptozotocin. After two months blood samples were collected for assessment of serum triglycerides, total, high density lipoprotein, and low density lipoprotein cholesterol, fasting blood sugar, serum insulin, intercellular adhesion molecule-1, nitrite and nitrate, plasma hydrogen peroxide, glutathione peroxidase activity and percent of DNA damage. The result showed that supplementation with almond oil and diosmin exerted an anti atherogenic effect with amelioration of glycemic status along with decreased DNA damage in STZ induced diabetic rats, these effects are more pronounced in diabetic group treated almond oil.

Biographie de l'auteur

Mona Anwar, Prof. of Medical Biochemistry and Clinical Nutriyion. Medical Biochemistry Department, National Research Centre, Cairo, Egypt.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
3659573523
ISBN 13 
9783659573521
Reliure
Broché
Nombre de pages
112
Coordonnées du fabricant
non disponible
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