Mutational analysis of MDM2 Gene: Mutational analysis of MDM2 Gene in Hepatocellular Carcinoma - Couverture souple

Iqbal, Muhammad Naeem; Ali, Hafiz Muzaffar; Bhatti, Shahzad

9783659586033: Mutational analysis of MDM2 Gene: Mutational analysis of MDM2 Gene in Hepatocellular Carcinoma

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ISBN 10 : 365958603X ISBN 13 : 9783659586033

Editeur : LAP LAMBERT Academic Publishing, 2014

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HCC represents the fifth most prevalent cancer worldwide, and accounts for the top three cause of death in the Asia-Pacific region. The risk factor associated with HCC include age, sex, alcohol, diet, and infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). The incidence rate of HCC is plausibly linked to geographic area and geo-economic conditions; it is possible that gene polymorphism may be associated with the risk of HCC. PCR technique is used for the diagnosis of point mutation in the MDM2 gene. The point mutation at MDM2-SNP309 from T to G was detected which may be responsible for HCC in patients with HCV. This mutation also effect with the increase of age sex, because the frequency of mutation is more common in females as compared to the male. In these studies five cases shows the mutational changes for the allele T/G. The frequency of the mutated alleles is 10% for the mutations. So it is concluded that the mutation is responsible for HCC. So the study shows that the frequency of mutated T/G allele is more liable to cause the disease.

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�diteur: LAP LAMBERT Academic Publishing
Date d'�dition: 2014
Langue: anglais
ISBN 10: 365958603X
ISBN 13: 9783659586033
Reliure: Broch�
Nombre de pages: 72
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Mutational analysis of MDM2 Gene

Muhammad Naeem Iqbal|Hafiz Muzaffar Ali|Shahzad Bhatti

Edit� par LAP LAMBERT Academic Publishing, 2014

ISBN 10 : 365958603X ISBN 13 : 9783659586033

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Iqbal Muhammad NaeemMuhammad Naeem IqbalPhD Scholar China Agriculture University, Beijing, China.Ex PhD Scholar UVAS, Lahore, Pakistan.M.D: Iqbal Science Academy Noorkot, Pakistan.HCC represents the fifth most prevalent cancer wo. N� de r�f. du vendeur 5166713

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Mutational analysis of MDM2 Gene

Muhammad Naeem Iqbal

Edit� par LAP LAMBERT Academic Publishing Aug 2014, 2014

ISBN 10 : 365958603X ISBN 13 : 9783659586033

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -HCC represents the fifth most prevalent cancer worldwide, and accounts for the top three cause of death in the Asia-Pacific region. The risk factor associated with HCC include age, sex, alcohol, diet, and infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). The incidence rate of HCC is plausibly linked to geographic area and geo-economic conditions; it is possible that gene polymorphism may be associated with the risk of HCC. PCR technique is used for the diagnosis of point mutation in the MDM2 gene. The point mutation at MDM2-SNP309 from T to G was detected which may be responsible for HCC in patients with HCV. This mutation also effect with the increase of age sex, because the frequency of mutation is more common in females as compared to the male. In these studies five cases shows the mutational changes for the allele T/G. The frequency of the mutated alleles is 10% for the mutations. So it is concluded that the mutation is responsible for HCC. So the study shows that the frequency of mutated T/G allele is more liable to cause the disease. 72 pp. Englisch. N� de r�f. du vendeur 9783659586033

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Mutational analysis of MDM2 Gene : Mutational analysis of MDM2 Gene in Hepatocellular Carcinoma

Muhammad Naeem Iqbal

Edit� par LAP LAMBERT Academic Publishing, 2014

ISBN 10 : 365958603X ISBN 13 : 9783659586033

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - HCC represents the fifth most prevalent cancer worldwide, and accounts for the top three cause of death in the Asia-Pacific region. The risk factor associated with HCC include age, sex, alcohol, diet, and infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). The incidence rate of HCC is plausibly linked to geographic area and geo-economic conditions; it is possible that gene polymorphism may be associated with the risk of HCC. PCR technique is used for the diagnosis of point mutation in the MDM2 gene. The point mutation at MDM2-SNP309 from T to G was detected which may be responsible for HCC in patients with HCV. This mutation also effect with the increase of age sex, because the frequency of mutation is more common in females as compared to the male. In these studies five cases shows the mutational changes for the allele T/G. The frequency of the mutated alleles is 10% for the mutations. So it is concluded that the mutation is responsible for HCC. So the study shows that the frequency of mutated T/G allele is more liable to cause the disease. N� de r�f. du vendeur 9783659586033

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Mutational analysis of MDM2 Gene

Muhammad Naeem Iqbal

Edit� par LAP LAMBERT Academic Publishing Aug 2014, 2014

ISBN 10 : 365958603X ISBN 13 : 9783659586033

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -HCC represents the fifth most prevalent cancer worldwide, and accounts for the top three cause of death in the Asia-Pacific region. The risk factor associated with HCC include age, sex, alcohol, diet, and infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV). The incidence rate of HCC is plausibly linked to geographic area and geo-economic conditions; it is possible that gene polymorphism may be associated with the risk of HCC. PCR technique is used for the diagnosis of point mutation in the MDM2 gene. The point mutation at MDM2-SNP309 from T to G was detected which may be responsible for HCC in patients with HCV. This mutation also effect with the increase of age sex, because the frequency of mutation is more common in females as compared to the male. In these studies five cases shows the mutational changes for the allele T/G. The frequency of the mutated alleles is 10% for the mutations. So it is concluded that the mutation is responsible for HCC. So the study shows that the frequency of mutated T/G allele is more liable to cause the disease.Books on Demand GmbH, �berseering 33, 22297 Hamburg 72 pp. Englisch. N� de r�f. du vendeur 9783659586033

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