Synthesis and Characterization of Dicoumarol based Cu-Complexes: Preparation of Novel ligands - Couverture souple

Dholariya, Hitesh R.; Tarpada, Umesh P.; Patel, Yogesh S.

 
9783659644627: Synthesis and Characterization of Dicoumarol based Cu-Complexes: Preparation of Novel ligands
Couverture souple
ISBN 10 : 3659644625 ISBN 13 : 9783659644627
Editeur : LAP LAMBERT Academic Publishing, 2014

Synopsis

Our prime objective is to prepare a series of copper complex compounds which possess enhance biological activity by introducing 4-hydroxycoumarins and fluoroquinolones segments together. In the present article, we have synthesized twelve novel ligands and their Cu (II) complexes. We have focused much on antimicrobial activity, antioxidant and antitubarcular activity. Results from antimicrobial activity revealed that Cu (II) complexes were found biologically active as compared to its ligands. Few of the complexes have been found more potent antimicrobial agent against gram positive bacteria. Results obtained from the in vitro anti-tubercular activity of all Cu (II) complexes indicated that, few compounds have been found more potent than that of standard drugs Ethambutol and Streptomycin. One compound has been emerged as the promising anti-tubercular member due to better activity as compared to Streptomycin. In vitro antioxidant activity of all the complexes exposed moderate to good ferric reducing power. One of the compounds showed good anti oxidant power.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Reseña del editor

Our prime objective is to prepare a series of copper complex compounds which possess enhance biological activity by introducing 4-hydroxycoumarins and fluoroquinolones segments together. In the present article, we have synthesized twelve novel ligands and their Cu (II) complexes. We have focused much on antimicrobial activity, antioxidant and antitubarcular activity. Results from antimicrobial activity revealed that Cu (II) complexes were found biologically active as compared to its ligands. Few of the complexes have been found more potent antimicrobial agent against gram positive bacteria. Results obtained from the in vitro anti-tubercular activity of all Cu (II) complexes indicated that, few compounds have been found more potent than that of standard drugs Ethambutol and Streptomycin. One compound has been emerged as the promising anti-tubercular member due to better activity as compared to Streptomycin. In vitro antioxidant activity of all the complexes exposed moderate to good ferric reducing power. One of the compounds showed good anti oxidant power.

Biografía del autor

Dr. Hitesh R. Dholariya has specialty in the Inorganic complexes synthesis. He has Ph.D. academic qualification as well as have a good industrial experiments. Dr. Umesh P. Tarpada and Dr. Yogesh S. Patel have also good academic qualification with Doctoral degree in the field of organic chemistry and polymer chemistry respectively.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2014
Langue
anglais
ISBN 10 
3659644625
ISBN 13 
9783659644627
Reliure
Tapa blanda
Nombre de pages
68
Coordonnées du fabricant
non disponible
Personne responsable
non disponible