Cette étude a étudié les effets toxiques du benzène sur les fonctions hépatiques et rénales, l'image sanguine complète, les immunoglobulines et certaines enzymes antioxydantes en mettant l'accent sur le trans urinaire, l'acide trans-muconique (t, t-MA) comme biomarqueur de l'exposition au benzène, compte tenu de l'influence de la fumée de cigarette. Quatre-vingt un travailleurs (61 hommes et 20 femmes) ont été exposés au benzène, tandis que 83 sujets (55 hommes et 28 femmes) représentent un groupe témoin ont également été inclus. Des échantillons de sang ont été prélevés pour la détermination de l'alanine aminotransférase (ALT), de l'asparatate aminotransférate (AST), de la gamma glutamyl transférase (GGT) et de la phosphatase alcaline (ALP). Outre la détermination de l'urée et de la créatinine. Les immunoglobulines (IgG, IgA et IgM), le malondialdéhyde (MDA) et l'enzyme antioxydante (SOD et catalase) ont été estimées. De plus, le t-MA urinaire a été déterminé par chromatographie liquide haute performance (HPLC). Les résultats ont révélé une augmentation des valeurs des enzymes hépatiques et des IgM sériques avec une diminution des niveaux d'IgG et d'IgA. Une augmentation du niveau d'acide muconique t, t et MDA a également été détectée. Les niveaux d'éléments sanguins (globules blancs, globules rouges et plaquettes), SOD, catalase et GSH ont été diminués.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This study investigated the toxic effects of benzene on the liver and kidney functions, complete blood picture, immunoglobulins and some antioxidant enzymes with emphasis of urinary trans, trans-muconic acid (t,t-MA)as a biomarker of benzene exposure, considering the influence of cigarette smoke. Eighty one workers (61 males and 20 females) have been exposed to benzene, while 83 subjects (55males and 28 females) represent a control group were also included. Blood samples were taken for the determination of alanine aminotransferase (ALT), asparatate aminotransferate (AST), Gamma glutamyl transferase (GGT), and alkaline phosphatase (ALP). Beside the determination of both urea and creatinine. Immunoglobulins (IgG, IgA and IgM), Malondialdehyde(MDA)and antioxidants enzyme (SOD and catalase) were estimated. Also the urinary t,t-MA was determined by high performance liquid chromatography (HPLC). Results revealed an increased in the values of the liver enzymes and serum IgM with decreased levels of IgG and IgA. Also an increase in the level of t,t muconic acid and MDA was detected. The levels of blood elements (WBCs, RBCs and platelets), SOD, catalase and GSH were decreased. 156 pp. Englisch. N° de réf. du vendeur 9783659665684
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This study investigated the toxic effects of benzene on the liver and kidney functions, complete blood picture, immunoglobulins and some antioxidant enzymes with emphasis of urinary trans, trans-muconic acid (t,t-MA)as a biomarker of benzene exposure, considering the influence of cigarette smoke. Eighty one workers (61 males and 20 females) have been exposed to benzene, while 83 subjects (55males and 28 females) represent a control group were also included. Blood samples were taken for the determination of alanine aminotransferase (ALT), asparatate aminotransferate (AST), Gamma glutamyl transferase (GGT), and alkaline phosphatase (ALP). Beside the determination of both urea and creatinine. Immunoglobulins (IgG, IgA and IgM), Malondialdehyde(MDA)and antioxidants enzyme (SOD and catalase) were estimated. Also the urinary t,t-MA was determined by high performance liquid chromatography (HPLC). Results revealed an increased in the values of the liver enzymes and serum IgM with decreased levels of IgG and IgA. Also an increase in the level of t,t muconic acid and MDA was detected. The levels of blood elements (WBCs, RBCs and platelets), SOD, catalase and GSH were decreased. N° de réf. du vendeur 9783659665684
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This study investigated the toxic effects of benzene on the liver and kidney functions, complete blood picture, immunoglobulins and some antioxidant enzymes with emphasis of urinary trans, trans-muconic acid (t,t-MA)as a biomarker of benzene exposure, considering the influence of cigarette smoke. Eighty one workers (61 males and 20 females) have been exposed to benzene, while 83 subjects (55males and 28 females) represent a control group were also included. Blood samples were taken for the determination of alanine aminotransferase (ALT), asparatate aminotransferate (AST), Gamma glutamyl transferase (GGT), and alkaline phosphatase (ALP). Beside the determination of both urea and creatinine. Immunoglobulins (IgG, IgA and IgM), Malondialdehyde(MDA)and antioxidants enzyme (SOD and catalase) were estimated. Also the urinary t,t-MA was determined by high performance liquid chromatography (HPLC). Results revealed an increased in the values of the liver enzymes and serum IgM with decreased levels of IgG and IgA. Also an increase in the level of t,t muconic acid and MDA was detected. The levels of blood elements (WBCs, RBCs and platelets), SOD, catalase and GSH were decreased.Books on Demand GmbH, Überseering 33, 22297 Hamburg 156 pp. Englisch. N° de réf. du vendeur 9783659665684
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Taschenbuch. Etat : Neu. Toxicological Effects of Occupational Exposure to Benzene | Eman Shahy (u. a.) | Taschenbuch | 156 S. | Englisch | 2015 | LAP Lambert Academic Publishing | EAN 9783659665684 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. N° de réf. du vendeur 104749654
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