Articles liés à Synthetic Bioactive Morpholine Based 1,3,4-Oxadiazole...

Synthetic Bioactive Morpholine Based 1,3,4-Oxadiazole Scaffolds: Synthesis of morpholine based 2,5-disubtituted 1,3,4-oxadiazoles - Couverture souple

Rehman, Aziz-ur-

 
9783659709548: Synthetic Bioactive Morpholine Based 1,3,4-Oxadiazole Scaffolds: Synthesis of morpholine based 2,5-disubtituted 1,3,4-oxadiazoles
Couverture souple
ISBN 10 : 3659709549 ISBN 13 : 9783659709548
Editeur : LAP LAMBERT Academic Publishing, 2015

Synopsis

The presented research work comprises of synthesis, spectral analysis and biological screening of some new acetamides/sulfides bearing substituted-1,3,4-Oxadiazole and morpholine moieties. The acetamide, 1,3,4-oxadiazole and morpholine moieties are important functionalities because of their broad range of known pharmacological activities. Synthetic approaches were utilized to synthesize poly-functional compounds. The main intention of the present research work was to design and synthesize some new poly-functional compounds having 1,3,4-oxadiazole and acetamide or 1,3,4-oxadiazole, morpholine and sulfide or 1,3,4-oxadiazole, morpholine and acetamide moieties together in one molecule. It was assumed that 2,5-disubstituted-1,3,4-oxadiazol ring along with the potential morpholine moiety and acetamide/sulfide functionality will enhance the activity of the molecule. Keeping in sight the broad diversity of biological activitites, some of the synthesized compounds were checked for their antibacaterial, hemolytic and antifungal screening. Some of compounds were found to be active and showed interesting results as compared to reference standard drugs.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The presented research work comprises of synthesis, spectral analysis and biological screening of some new acetamides/sulfides bearing substituted-1,3,4-Oxadiazole and morpholine moieties. The acetamide, 1,3,4-oxadiazole and morpholine moieties are important functionalities because of their broad range of known pharmacological activities. Synthetic approaches were utilized to synthesize poly-functional compounds. The main intention of the present research work was to design and synthesize some new poly-functional compounds having 1,3,4-oxadiazole and acetamide or 1,3,4-oxadiazole, morpholine and sulfide or 1,3,4-oxadiazole, morpholine and acetamide moieties together in one molecule. It was assumed that 2,5-disubstituted-1,3,4-oxadiazol ring along with the potential morpholine moiety and acetamide/sulfide functionality will enhance the activity of the molecule. Keeping in sight the broad diversity of biological activitites, some of the synthesized compounds were checked for their antibacaterial, hemolytic and antifungal screening. Some of compounds were found to be active and showed interesting results as compared to reference standard drugs.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659709549
ISBN 13 
9783659709548
Reliure
Broché
Nombre de pages
176
Coordonnées du fabricant
non disponible
Personne responsable
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