Agent-based Modeling of Angiogenesis within Biomaterial Scaffolds - Couverture souple

Mehdizadeh, Hamidreza

 
9783659712890: Agent-based Modeling of Angiogenesis within Biomaterial Scaffolds
Couverture souple
ISBN 10 : 3659712892 ISBN 13 : 9783659712890
Editeur : LAP LAMBERT Academic Publishing, 2015

Synopsis

This book highlights the development of a multi-layer agent-based framework for modeling angiogenesis within 3D biodegradable biomaterial scaffolds. Throughout this computational study, experimental methods have complemented model development by providing information for determining model parameters and results for validating simulation outcomes. This integration of simulation results and experimental studies facilitated development of a simulation framework that can be used to improve blood vessel formation in engineered tissues. While there has been significant interest in the therapeutic control of angiogenesis in tissue engineering scaffolds, every hypothesis made or every therapeutic approach proposed requires being tested using experimental laboratory methods and time consuming and costly animal models. The developed computational framework will assist in designing and testing pro-angiogenic scaffolds that support rapid and extensive vascularization, providing an efficient in silico testing environment for evaluating new ideas, without the need for performing costly experiments.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This book highlights the development of a multi-layer agent-based framework for modeling angiogenesis within 3D biodegradable biomaterial scaffolds. Throughout this computational study, experimental methods have complemented model development by providing information for determining model parameters and results for validating simulation outcomes. This integration of simulation results and experimental studies facilitated development of a simulation framework that can be used to improve blood vessel formation in engineered tissues. While there has been significant interest in the therapeutic control of angiogenesis in tissue engineering scaffolds, every hypothesis made or every therapeutic approach proposed requires being tested using experimental laboratory methods and time consuming and costly animal models. The developed computational framework will assist in designing and testing pro-angiogenic scaffolds that support rapid and extensive vascularization, providing an efficient in silico testing environment for evaluating new ideas, without the need for performing costly experiments.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659712892
ISBN 13 
9783659712890
Reliure
Broché
Nombre de pages
256
Coordonnées du fabricant
non disponible
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