Flavones: A Polyfunctional Weapon Against Multiple Diseases: Recent advances in the discovery and development of Flavones as Poly-functional Agents - Couverture souple

Silakari, Om; Singh, Manjinder; Kaur, Maninder

 
9783659759079: Flavones: A Polyfunctional Weapon Against Multiple Diseases: Recent advances in the discovery and development of Flavones as Poly-functional Agents
Couverture souple
ISBN 10 : 3659759074 ISBN 13 : 9783659759079
Editeur : LAP LAMBERT Academic Publishing, 2015

Synopsis

Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders, etc. Also, flavonoids are found to have an effect on several mammalian enzymes like protein kinases that regulate multiple cell signaling pathways and alterations in multiple cellular signaling pathways are frequently found in many diseases. Flavones have been an indispensable anchor for the development of new therapeutic agents. Due to the wide range of biological activities of flavones, their structure–activity relationships have generated interest among medicinal chemists. The outstanding development of flavones derivatives in diverse diseases in very short span of time proves its magnitude for medicinal chemistry research. The present review gives detail about the structural requirement of flavone derivatives for various pharmacological activities. This information may provide an opportunity to scientists of medicinal chemistry discipline to design selective, optimize as well as poly-functional flavone derivatives for the treatment of multi-factorial diseases.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders, etc. Also, flavonoids are found to have an effect on several mammalian enzymes like protein kinases that regulate multiple cell signaling pathways and alterations in multiple cellular signaling pathways are frequently found in many diseases. Flavones have been an indispensable anchor for the development of new therapeutic agents. Due to the wide range of biological activities of flavones, their structure–activity relationships have generated interest among medicinal chemists. The outstanding development of flavones derivatives in diverse diseases in very short span of time proves its magnitude for medicinal chemistry research. The present review gives detail about the structural requirement of flavone derivatives for various pharmacological activities. This information may provide an opportunity to scientists of medicinal chemistry discipline to design selective, optimize as well as poly-functional flavone derivatives for the treatment of multi-factorial diseases.

Biographie de l'auteur

Dr. Om Silakari is working as an Assistant Professor at Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala. His research area includes computer-aided drug designing and the synthesis of lead molecules against different molecular targets. He has published 56 articles in international journals.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659759074
ISBN 13 
9783659759079
Reliure
Broché
Nombre de pages
140
Coordonnées du fabricant
non disponible
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