Insulin Resistance using HOMA model in Obstructive Sleep Apnea - Couverture souple

Azman Mawaddah; Zulkepli Siti Zulaili; Mohamed Abdullah Sani

 
9783659763366: Insulin Resistance using HOMA model in Obstructive Sleep Apnea
Couverture souple
ISBN 10 : 3659763365 ISBN 13 : 9783659763366
Editeur : LAP Lambert Academic Publishing, 2015

Synopsis

Obstructive sleep apnea (OSA) is a common disease and is associated with significant cardiovascular, cerebrovascular, and metabolic complications. Current evidences show inconclusive association between OSA and insulin resistance (IR). This study aims to examine possible correlation between OSA parameters and IR. A total of 62 patients underwent PSG within the study period, of which 16 patients were excluded due to abnormal fasting blood sugar. Information on patients' medical illnesses, medications, and Epworth sleepiness scale (ESS) was obtained. Patients' body mass index (BMI), neck circumference, and waist circumference (WC) were measured. Blood samples were collected after 8 hours of fasting to measure HOMA-IR value. Overnight PSG was performed for all patients. Data was recorded and analyzed. The prevalence of IR in OSA patients was 64.3%. There was significant correlation between OSA parameters (apnea-hypopnea index, ESS, BMI, and WC) and HOMA-IR with correlation coefficient of 0.529, 0.224, 0.261, and 0.354, respectively. In conclusion, A linear correlation exists between OSA parameters and IR concluding a definite causal link between OSA and IR.

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Éditeur
LAP Lambert Academic Publishing
Date d'édition
2015
Langue
anglais
ISBN 10 
3659763365
ISBN 13 
9783659763366
Reliure
Broché
Nombre de pages
60
Coordonnées du fabricant
non disponible
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